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  • Primary Antibodies ›
  • TNFRSF11B Antibodies

Abnova

TNFRSF11B Polyclonal Antibody, MaxPab™

View all (24) TNFRSF11B antibodies

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Protocols
Questions & Answers

Cite TNFRSF11B Polyclonal Antibody, MaxPab™

  • Antibody Testing Data (2)
TNFRSF11B Antibody in Western Blot (WB)
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TNFRSF11B Antibody in Western Blot (WB)
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TNFRSF11B Antibody (H00004982-B02P) in WB

Western Blot analysis of TNFRSF11B expression in transfected 293T cell line (H00004982-T01) by TNFRSF11B MaxPab polyclonal antibody.

Lane 1: TNFRSF11B transfected lysate(44.11 KDa).
Lane 2: Non-transfected lysate.
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TNFRSF11B Antibody in Western Blot (WB)
TNFRSF11B Antibody in Western Blot (WB)
TNFRSF11B Polyclonal Antibody, MaxPab™

Product Details

H00004982-B02P

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG

Class

Polyclonal

Type

Antibody

Immunogen

TNFRSF11B (AAH30155.1, 1 a.a. approximately 401 a.a) full-length human protein.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MNNLLCCALV FLDISIKWTT QETFPPKYLH YDEETSHQLL CDKCPPGTYL KQHCTAKWKT VCAPCPDHYY TDSWHTSDEC LYCSPVCKEL QYVKQECNRT HNRVCECKEG RYLEIEFCLK HRSCPPGFGV VQAGTPERNT VCKRCPDGFF SNETSSKAPC RKHTNCSVFG LLLTQKGNAT HDNICSGNSE STQKCGIDVT LCEEAFFRFA VPTKFTPNWL SVLVDNLPGT KVNAESVERI KRQHSSQEQT FQLLKLWKHQ NKDQDIVKKI IQDIDLCENS VQRHIGHANL TFEQLRSLME SLPGKKVGAE DIEKTIKACK PSDQILKLLS LWRIKNGDQD TLKGLMHALK HSKTYHFPKT VTQSLKKTIR FLHSFTMYKL YQKLFLEMIG NQVQSVKISC L

Target Information

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: MGC29565; Osteoclastogenesis inhibitory factor; Osteoprotegerin; soluble OPG; soluble Osteoprotegerin; sOPG; Tumor necrosis factor receptor superfamily member 11B; tumor necrosis factor receptor superfamily, member 11b

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Gene Aliases: OCIF; OPG; PDB5; TNFRSF11B; TR1

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UniProt ID: (Human) O00300

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Entrez Gene ID: (Human) 4982

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Function(s)
receptor activity tumor necrosis factor-activated receptor activity cytokine activity
Process(es)
skeletal system development inflammatory response immune response signal transduction response to nutrient extracellular matrix organization response to magnesium ion response to lipopolysaccharide tumor necrosis factor-mediated signaling pathway regulation of cell proliferation negative regulation of odontogenesis of dentin-containing tooth response to drug regulation of apoptotic process positive regulation of MAPK cascade response to estrogen negative regulation of bone resorption response to arsenic-containing substance apoptotic signaling pathway
It has to be done as per old AB suggested Products section.
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