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  • TLR6 Antibodies

Fabgennix

TLR6 Polyclonal Antibody

View all (25) TLR6 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite TLR6 Polyclonal Antibody

  • Antibody Testing Data (1)
TLR6 Antibody in Immunohistochemistry (IHC)
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TLR6 Antibody in Immunohistochemistry (IHC)
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TLR6 Antibody (TLR-601AP) in IHC

Rat Spleen- TLR6 Primary Antibody: TLR-601AP; 1:100 dilution in IHC Blocking Buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40x magnification on Leica DM4000. FFPE section. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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TLR6 Antibody in Immunohistochemistry (IHC)
TLR6 Polyclonal Antibody

Product Details

TLR-601AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

Immunohistochemistry (IHC)

1:50-1:250
-

ELISA (ELISA)

1:10,000
-

Immunoprecipitation (IP)

1:50-1:250
-
Product Specifications

Species Reactivity

Cat, Human, Mouse, Pig, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide taken within amino acid region 195-225 on human TLR6 protein.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5-1.5 mg/mL

Purification

Affinity chromatography

Storage buffer

proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

TLR6 (Toll-like receptor 6) is a member of the toll-like receptor family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved and share structural and functional similarities. TLRs recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR6 functionally interacts with TLR2 to mediate cellular response to bacterial lipoproteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CD antigen 286; CD286; Toll-like receptor 6

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Gene Aliases: CD286; TLR-6; TLR6

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UniProt ID: (Human) Q9Y2C9, (Mouse) Q9EPW9

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Entrez Gene ID: (Pig) 396621, (Cat) 493662, (Human) 10333, (Mouse) 21899, (Rat) 305353

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Function(s)
receptor activity transmembrane signaling receptor activity protein binding Toll-like receptor 2 binding lipopeptide binding diacyl lipopeptide binding protein heterodimerization activity
Process(es)
microglial cell activation toll-like receptor signaling pathway immune system process MyD88-dependent toll-like receptor signaling pathway inflammatory response immune response signal transduction response to bacterial lipoprotein toll-like receptor 6 signaling pathway T-helper 1 type immune response detection of diacyl bacterial lipopeptide positive regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of JUN kinase activity positive regulation of interleukin-12 biosynthetic process innate immune response positive regulation of interleukin-6 biosynthetic process nitric oxide metabolic process regulation of cytokine secretion cellular response to diacyl bacterial lipopeptide activation of NF-kappaB-inducing kinase activity toll-like receptor TLR6:TLR2 signaling pathway defense response to bacterium interleukin-1 beta secretion positive regulation of NLRP3 inflammasome complex assembly
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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