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  • Primary Antibodies ›
  • TFR2 Antibodies

OriGene

TFR2 Monoclonal Antibody (OTI2B4), TrueMAB™

View all (14) TFR2 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite TFR2 Monoclonal Antibody (OTI2B4), TrueMAB™

  • Antibody Testing Data (4)
TFR2 Antibody in Immunocytochemistry (ICC/IF)
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TFR2 Antibody in Immunocytochemistry (ICC/IF)
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FIGURE: 1 / 4

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TFR2 Antibody (TA504563) in ICC/IF

Anti-TFR2 mouse monoclonal antibody (TA504563) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TFR2(RC220060). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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TFR2 Antibody in Immunocytochemistry (ICC/IF)
TFR2 Antibody in Western Blot (WB)
TFR2 Antibody in Western Blot (WB)
TFR2 Antibody in Flow Cytometry (Flow)
TFR2 Monoclonal Antibody (OTI2B4), TrueMAB™

Product Details

TA504563

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunocytochemistry (ICC/IF)

1:100
-

Flow Cytometry (Flow)

1:100
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

OTI2B4

Immunogen

Full length human recombinant protein of human TFR2 produced in HEK293T cell.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: MGC126368; TfR2; Transferrin receptor protein 2

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Gene Aliases: HFE3; TFR2; TFRC2; Trfr2

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UniProt ID: (Human) Q9UP52, (Rat) B2GUY2, (Mouse) Q9JKX3

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Entrez Gene ID: (Human) 7036, (Rat) 288562, (Mouse) 50765

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Function(s)
glycoprotein binding transferrin receptor activity protein binding co-receptor binding molecular_function
Process(es)
biological_process iron ion homeostasis cellular iron ion homeostasis receptor-mediated endocytosis iron ion transport response to iron ion transferrin transport positive regulation of endocytosis positive regulation of transcription from RNA polymerase II promoter cellular response to iron ion positive regulation of peptide hormone secretion ferrous iron import into cell positive regulation of protein maturation
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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