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Invitrogen
TESPA1 Polyclonal Antibody
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FIGURE: 1 / 7
TESPA1 Antibody (PA5-85981) in ICC/IF
Product Details
PA5-85981
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
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Purification
Storage buffer
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RRID
Target Information
TESPA1 is a critical component of the TCR signalosome and is essential for T cell selection and maturation through the regulation of TCR signaling during T cell development. TESPA1 encodes a protein of 458 amino acids and is highly conserved among vertebrate species. TESPA1 expression was tightly regulated during T cell development, with highest expression at the DP stage. TESPA1 deficiency resulted in failure of positive selection and substantially fewer of CD4+ and CD8+ SP cells in the thymus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Protein TESPA1; thymocyte expressed; Thymocyte-expressed positive selection-associated protein 1
Gene Aliases: 5830405N20Rik; A430001F24Rik; AI450549; HSPC257; KIAA0748; TESPA1
UniProt ID: (Human) A2RU30, (Mouse) Q3U132
Entrez Gene ID: (Human) 9840, (Mouse) 67596
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