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  • Syntaxin 1 Antibodies

Invitrogen

Syntaxin 1 Recombinant Mouse Monoclonal Antibody (SP6)

View all (31) Syntaxin 1 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite Syntaxin 1 Recombinant Mouse Monoclonal Antibody (SP6)

  • Antibody Testing Data (3)
Syntaxin 1 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
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Syntaxin 1 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
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Syntaxin 1 Antibody (MA5-47883) in IHC (PFA)

Immunohistochemistry (PFA fixed) analysis of Syntaxin 1 in formalin fixed rabbit kidney slices using Syntaxin 1 Recombinant Monoclonal Antibody (Product # MA5-47883) at a concentration of 3 µg/mL. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Syntaxin 1 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
Syntaxin 1 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
Syntaxin 1 Antibody in Western Blot (WB)
Syntaxin 1 Recombinant Mouse Monoclonal Antibody (SP6)

Product Details

MA5-47883

Applications
Tested Dilution
Publications

Western Blot (WB)

3 µg/mL
-

Immunohistochemistry (PFA fixed) (IHC (PFA))

3 µg/mL
-
Product Specifications

Species Reactivity

Bovine, Dog, Guinea pig, Hamster, Human, Pig, Rabbit, Rat

Host/Isotype

Mouse / IgG1, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

SP6

Immunogen

Synaptic vesicle-containing fractions immunoprecipitated from human brain homogenates.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.02% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_3074327

Product Specific Information

Specificity: This antibody binds to native and denatured syntaxin.

Target Information

Syntaxin 1 is a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Neuron-specific antigen HPC-1; P35A; STX1B; STX1B1; STX1B2; STXA1; Synaptotagmin-associated 35 kDa protein; syntaxin 1A (brain); syntaxin 1A (brain)-like; syntaxin-1; Syntaxin-1A; Syntaxin-1B1; Syntaxin-1B2

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Gene Aliases: BOS_23037; HPC-1; I79_007242; P35-1; Sap; STX1; STX1A; SYN1A

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UniProt ID: (Human) Q16623, (Bovine) P32850, (Rat) P32851

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Entrez Gene ID: (Rabbit) 100008772, (Human) 6804, (Bovine) 788566, (Dog) 100855965, (Chinese hamster) 100759989, (Rat) 116470

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Function(s)
SNARE binding glycoprotein binding SNAP receptor activity protein binding myosin binding calcium channel inhibitor activity chloride channel inhibitor activity kinase binding protein domain specific binding protein binding, bridging myosin head/neck binding ATP-dependent protein binding ion channel binding protein heterodimerization activity protein N-terminus binding calcium-dependent protein binding
Process(es)
positive regulation of neurotransmitter secretion intracellular protein transport neurotransmitter secretion response to gravity positive regulation of norepinephrine secretion regulation of synaptic vesicle priming glutamate secretion synaptic vesicle docking synaptic vesicle fusion to presynaptic active zone membrane secretion by cell positive regulation of catecholamine secretion positive regulation of calcium ion-dependent exocytosis vesicle docking regulation of insulin secretion positive regulation of excitatory postsynaptic potential neurotransmitter transport exocytosis chemical synaptic transmission calcium ion regulated exocytosis regulation of exocytosis positive regulation of exocytosis
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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