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Proteintech
Synaptopodin Polyclonal Antibody
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Product Details
21064-1-AP
Species Reactivity
Published species
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Immunogen sequence: SPPSYSVLY PSSDPKSSHL KGQAVPASKT GILEESMARR GSRKSMFTFV EKPKVTPNPD LLDLVQTADE KRRQRDQGEV GVEEEPFALG AEASNFQQEP APRDRASPAA AEEVVPEWAS CLKSPRIQAK PKPKPNQNLS EASGKGAELY ARRQSRMEKY VIESSSHTPE LARCPSPTMS LPSSWKYPTN APGAFRVASR SPARTPPASL YHGYLPENGV LRPEPTKQPP YQLRPSLFVL SPIKEPAKVS PRAASPAKPS SLDLVPNLPK GALPPSPALP RPSRSSPGLY TSPGQDSLQP TAVSPPYGGD ISPVSPSRAW SPRAKQAPRP SFSTRNAGIE AQVWKPSFCF K (580-929 aa encoded by BC146665)
Target Information
SYNPO (Synaptopodin) is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Synaptopodin
Gene Aliases: 9030217H17Rik; 9130229N11; 9330140I15Rik; AW046661; KIAA1029; SYNPO
UniProt ID: (Human) Q8N3V7, (Rat) Q9Z327
Entrez Gene ID: (Human) 11346, (Rat) 60324, (Mouse) 104027
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