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Invitrogen
Synapsin 1 Polyclonal Antibody
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FIGURE: 1 / 24
Synapsin 1 Antibody (A-6442) in ICC/IF
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.jpg?time=20250104?time=20250104 "Synapsin 1 Antibody (A-6442) in IHC")
Product Details
A-6442
Species Reactivity
Published species
Host/Isotype
Class
Type
Immunogen
Conjugate
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Product Specific Information
This antibody has little or no activity against Synapsin II.
Storage and reconstitution: when stored at -20°C or below, the lyophilized antibody should retain full activity for over one year. Reconstitute using 50 µL PBS, pH 7.4, to yield a 0.2 mg/mL solution. If storing at 0-4°C, add sodium azide to a final concentration of 2mM. For longer storage, divide the solution into aliquots and freeze at -20°C, avoiding freeze/thaw cycles.
Target Information
SYN1 (synapsin 1) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins that associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains and are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. Synapsin 1 plays a role in regulation of axonogenesis and synaptogenesis. It serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Brain protein 4.1; synapsin 1; Synapsin I; Synapsin-1; truncated synapsin 1-S
Gene Aliases: BOS_25913; Syn-1; SYN1; Syn1-S; SYN1a; SYN1b; SYNI
UniProt ID: (Bovine) P17599, (Human) P17600, (Rat) P09951, (Mouse) O88935
Entrez Gene ID: (Bovine) 281510, (Human) 6853, (Rat) 24949, (Mouse) 20964
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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