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Bioss
Sema3F/semaphorin 3F Polyclonal Antibody
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FIGURE: 1 / 3
Sema3F/semaphorin 3F Antibody (BS-1122R) in IHC (P)
Product Details
BS-1122R
Species Reactivity
Host/Isotype
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Type
Immunogen
Conjugate
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Target Information
The semaphorins are a family of proteins that are involved in signaling. All the family members have a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues (Kolodkin et al., 1993 [PubMed 8269517]). Sequence comparisons have grouped the secreted semaphorins into 3 general classes, all of which also have an immunoglobulin domain. The semaphorin III family, consisting of human semaphorin III (SEMA3A; MIM 603961), chicken collapsin, and mouse semaphorins A, D, and E, all have a basic domain at the C terminus. Chicken collapsin contributes to path finding by axons during development by inhibiting extension of growth cones (Luo et al., 1993 [PubMed 8402908]) through an interaction with a collapsin response mediator protein of relative molecular mass 62K (CRMP62) (Goshima et al., 1995 [PubMed 7637782]), a putative homolog of an axonal guidance associated UNC33 gene product (MIM 601168). SEMA3F is a secreted member of the semaphorin III family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, 3F; Sema III/F; Sema IV; semaphorin 3F; semaphorin III/F; Semaphorin IV; Semaphorin-3F
Gene Aliases: SEMA-IV; SEMA3F; SEMA4; SemaIV; SEMAK
UniProt ID: (Human) Q13275, (Mouse) O88632
Entrez Gene ID: (Human) 6405, (Mouse) 20350, (Rat) 315996
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