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Invitrogen
Sarcomeric alpha Actin Monoclonal Antibody (5C5)
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Product Details
MA1-21597
Species Reactivity
Published species
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
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RRID
Product Specific Information
MA1-21597 detects alpha sarcomeric actin in bovine, guinea pig,human, rabbit, rat, fish, pig, snake, Xenopus and sheep samples.
Target Information
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: act; actg; Actin, alpha cardiac muscle 1; Actin, alpha skeletal muscle; actin, alpha, cardiac muscle 1; Actin, aortic smooth muscle; Alpha-actin-1; Alpha-actin-2; Alpha-cardiac actin; alpha-sma; alpha-smooth muscle actin; beta-actin; Cell growth-inhibiting gene 46 protein; cytoplasmic beta-actin; dfna20; dfna26; MGC75587; nemaline myopathy type 3
Gene Aliases: AAT6; ACTA; ACTA1; ACTA2; ACTC; ACTC1; ACTSA; ACTVS; ASD5; ASMA; CFTD; CFTD1; CFTDM; CMD1R; CMH11; GIG46; LVNC4; MPFD; MYMY5; NEM1; NEM2; NEM3; SHPM
UniProt ID: (Human) P68133, (Rabbit) P62740, (Human) P62736, (Human) P68032, (Rabbit) P68135
Entrez Gene ID: (Human) 58, (Rabbit) 100009271, (Human) 59, (Human) 70, (Rabbit) 100340339, (Rabbit) 100009506
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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