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  • Primary Antibodies ›
  • SUMO2/SUMO3/SUMO4 Antibodies

Invitrogen

SUMO2/SUMO3/SUMO4 Polyclonal Antibody

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite SUMO2/SUMO3/SUMO4 Polyclonal Antibody

  • Antibody Testing Data (3)
SUMO2/SUMO3/SUMO4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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SUMO2/SUMO3/SUMO4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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SUMO2/SUMO3/SUMO4 Antibody (PA5-103276) in IHC (P)

Immunohistochemistry analysis of SUMO2/SUMO3/SUMO4 in human esophageal cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with SUMO2/SUMO3/SUMO4 polyclonal antibody (Product # PA5-103276) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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SUMO2/SUMO3/SUMO4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
SUMO2/SUMO3/SUMO4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
SUMO2/SUMO3/SUMO4 Antibody in Western Blot (WB)
SUMO2/SUMO3/SUMO4 Polyclonal Antibody

Product Details

PA5-103276

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:3,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human SUMO2(Accession P61956), corresponding to amino acid residues M1-Q51.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2815973

Product Specific Information

Antibody detects endogenous levels of total Sumo2/3/4.

Target Information

SUMO proteins and ubiquitin post translationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: HSMT3; insulin-dependent diabetes mellitus 5; sentrin 2; Sentrin-2; small ubiquitin-like modifier 4 protein; Small ubiquitin-like protein 4; Small ubiquitin-related modifier 2; Small ubiquitin-related modifier 3; Small ubiquitin-related modifier 4; SMT3 (supressor of mif two, 3) homolog 1; SMT3 homolog 1; SMT3 homolog 2; SMT3 suppressor of mif two 3 homolog 1; SMT3 suppressor of mif two 3 homolog 2; SMT3 suppressor of mif two 3 homolog 2-like; SMT3 suppressor of mif two 3 homolog 3; SMT3 suppressor of mif two 3 homolog 4; SMT3 supressor of mif two 3 homolog 2; Smt3A; Smt3B; SUMO-2; SUMO-3; SUMO-4; Ubiquitin-like protein SMT3A; Ubiquitin-like protein SMT3B

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Gene Aliases: 2810014B19Rik; D10Ertd345e; dJ281H8.4; HSMT3; IDDM5; SMT3A; SMT3B; SMT3H1; SMT3H2; SMT3H4; SUMO-2; SUMO-3; SUMO-4; SUMO2; SUMO3; SUMO4

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UniProt ID: (Human) P61956, (Human) P55854, (Human) Q6EEV6, (Rat) P61959, (Mouse) P61957, (Rat) Q5XIF4, (Mouse) Q9Z172

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Entrez Gene ID: (Human) 6613, (Human) 6612, (Human) 387082, (Rat) 690244, (Mouse) 170930, (Rat) 682787, (Rat) 499417, (Mouse) 20610

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Function(s)
protein binding protein tag ubiquitin protein ligase binding poly(A) RNA binding SUMO transferase activity
Process(es)
protein sumoylation positive regulation of proteasomal ubiquitin-dependent protein catabolic process cellular protein localization negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter global genome nucleotide-excision repair protein localization to nucleus positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
It has to be done as per old AB suggested Products section.
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