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Proteintech

STXBP1 Monoclonal Antibody (1B5B3)

View all (23) MUNC18 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite STXBP1 Monoclonal Antibody (1B5B3)

  • Antibody Testing Data (5)
STXBP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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STXBP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 5

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STXBP1 Antibody (67137-1-IG) in IHC (P)

Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 67137-1-Ig (STXBP1 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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STXBP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
STXBP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
STXBP1 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
STXBP1 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
STXBP1 Antibody in Western Blot (WB)

Product Details

67137-1-IG

Applications
Tested Dilution
Publications

Western Blot (WB)

1:10,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000
-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Pig, Rat

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

1B5B3

Immunogen

STXBP1 Fusion Protein Ag28605

Conjugate

Unconjugated Unconjugated Unconjugated
  • Biotin 
  • CoraLite 594
  • CoraLite Plus 488
  • Request custom conjugation

Form

Liquid

Concentration

1000 µg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Aliquoting is unnecessary for -20°C storage.

Target Information

This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: EIEE4; FLJ37475; hUNC18; MGC146482; minisatellite 10g detected by probe MMS10; munc-18c; MUNC18-1; N-Sec1; neuronal SEC1; p67; Protein unc-18 homolog 1; Protein unc-18 homolog A; rbSec1; rop; RP11-56D16.3; Syntaxin-binding protein 1; UNC-18 homolog; unc-18-1; Unc-18A; Unc18-1

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Gene Aliases: AI317162; AI326233; ANC18HA; MMS10-G; Ms10g; Munc-18a; MUNC18-1; N-sec1; NSEC1; NSEC1A; P67; Rb-sec1; RBSEC1; rbSec1A; rbSec1B; Sec1; STXBP1; Sxtbp1; UNC18; Unc18-1; UNC18A; Unc18h

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UniProt ID: (Human) P61764, (Mouse) O08599, (Rat) P61765

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Entrez Gene ID: (Human) 6812, (Mouse) 20910, (Rat) 25558

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Function(s)
SNARE binding protein binding syntaxin-1 binding protein kinase binding protein domain specific binding syntaxin binding identical protein binding poly(A) RNA binding protein N-terminus binding
Process(es)
platelet degranulation transport exocytosis vesicle docking involved in exocytosis neurotransmitter secretion neuromuscular synaptic transmission axon target recognition regulation of synaptic vesicle priming protein transport synaptic vesicle maturation vesicle-mediated transport synaptic vesicle fusion to presynaptic active zone membrane negative regulation of synaptic transmission, GABAergic negative regulation of neuron apoptotic process positive regulation of exocytosis positive regulation of calcium ion-dependent exocytosis protein stabilization long term synaptic depression platelet aggregation protein localization to plasma membrane glutamate secretion regulation of synaptic vesicle fusion to presynaptic membrane regulation of SNARE complex assembly
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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