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  • Primary Antibodies ›
  • STK39 Antibodies

Invitrogen

STK39 Polyclonal Antibody

View all (29) STK39 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite STK39 Polyclonal Antibody

  • Antibody Testing Data (4)
STK39 Antibody in Immunocytochemistry (ICC/IF)
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STK39 Antibody in Immunocytochemistry (ICC/IF)
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STK39 Antibody (PA5-111538) in ICC/IF

Immunofluorecent analysis of STK39 in human cell line Hep G2 using STK39 Polyclonal Antibody (Product # PA5-111538). Staining shows localization to nucleoplasm and vesicles. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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STK39 Antibody in Immunocytochemistry (ICC/IF)
STK39 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
STK39 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
STK39 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
STK39 Polyclonal Antibody

Product Details

PA5-111538

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein corresonding to Human STK39. Recombinant protein control fragment (Product #RP-104045).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2856948

Product Specific Information

Immunogen sequence: IVDDPKALKT LTFKLASGCD GSEIPDEVKL

Target Information

STK39 (STLK3) is involved in the cellular stress response pathway. STK39 is activated in response to hypotonic stress leading to phosphorylation of several cation-chloride-coupled co-transporters. STK39 activates the p38 MAP kinase pathway and its interaction with p38 decreases during cellular stress. STK39 acts as an intermediate in the response to cellular stress. STK39 is also an independent risk factor for hypertension in men and its intragenic SNPs can interact and function in the control of blood pressure.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: DCHT; DKFZp686K05124; proline-alanine-rich STE20-related kinase; serine threonine kinase 39 (STE20/SPS1 homolog, yeast); Serine/threonine-protein kinase 39; small intestine SPAK-like kinase; Ste-20-related kinase; Ste20-like protein kinase; STE20/SPS1 homolog; STE20/SPS1-related proline-alanine-rich protein kinase

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Gene Aliases: DCHT; PASK; SPAK; STK39

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UniProt ID: (Human) Q9UEW8

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Entrez Gene ID: (Human) 27347

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Function(s)
protein serine/threonine kinase activity receptor signaling protein serine/threonine kinase activity protein binding ATP binding protein kinase binding
Process(es)
negative regulation of protein phosphorylation protein phosphorylation response to stress regulation of blood pressure peptidyl-serine phosphorylation peptidyl-threonine phosphorylation signal transduction by protein phosphorylation intracellular signal transduction positive regulation of potassium ion transport regulation of inflammatory response cellular hypotonic response negative regulation of pancreatic juice secretion negative regulation of potassium ion transmembrane transporter activity negative regulation of potassium ion transmembrane transport regulation of ion homeostasis negative regulation of rubidium ion transport negative regulation of rubidium ion transmembrane transporter activity
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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