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  • STC1 Antibodies

OriGene

STC1 Monoclonal Antibody (OTI6D12), TrueMAB™

View all (17) STC1 antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite STC1 Monoclonal Antibody (OTI6D12), TrueMAB™

  • Antibody Testing Data (2)
STC1 Antibody in Western Blot (WB)
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STC1 Antibody in Western Blot (WB)
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STC1 Antibody (CF810025) in WB

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY STC1 (RC206573, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-STC1. (1. Positive lysates LY401098 (100 µg) and LC401098 (20 µg) can be purchased separately from OriGene. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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STC1 Antibody in Western Blot (WB)
STC1 Antibody in Western Blot (WB)
STC1 Monoclonal Antibody (OTI6D12), TrueMAB™

Product Details

CF810025

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-
Product Specifications

Species Reactivity

Dog, Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI6D12

Immunogen

Human recombinant protein fragment corresponding to amino acids 34-247 of human STC1 produced in E.coli.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 8% trehalose

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

Target Information

This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Stanniocalcin-1; STC-1

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Gene Aliases: STC; STC1

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UniProt ID: (Human) P52823, (Mouse) O55183, (Rat) P97574

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Entrez Gene ID: (Human) 6781, (Dog) 486112, (Mouse) 20855, (Rat) 81801

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Function(s)
hormone activity molecular_function
Process(es)
ossification endothelial cell morphogenesis growth plate cartilage axis specification cellular calcium ion homeostasis embryo implantation negative regulation of endothelial cell migration negative regulation of cell migration response to vitamin D chondrocyte proliferation regulation of anion transport decidualization negative regulation of calcium ion transport bone development cellular response to cAMP cellular response to glucocorticoid stimulus cellular response to hypoxia regulation of cardiac muscle cell contraction positive regulation of calcium ion import negative regulation of renal phosphate excretion cellular monovalent inorganic anion homeostasis response to organic cyclic compound
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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