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  • STAT6 Antibodies

Bethyl Laboratories

STAT6 Polyclonal Antibody

View all (64) STAT6 antibodies

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Datasheet
Protocols
Questions & Answers

Cite STAT6 Polyclonal Antibody

  • Antibody Testing Data (1)
STAT6 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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STAT6 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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STAT6 Antibody (IHC-00209) in IHC (P)

Detection of human STAT6 by immunohistochemistry. Sample: FFPE section of human mucinous ovarian carcinoma. Antibody: Affinity purified rabbit anti-STAT6 (Product # IHC-00209) used at a dilution of 1:250. Detection: DAB. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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STAT6 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
STAT6 Polyclonal Antibody

Product Details

IHC-00209

Applications
Tested Dilution
Publications

Immunohistochemistry (IHC)

1:100-1:500
-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:500
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Region between residues 600 and 650 of Human Signal Transducer and Activator of Transcription 6.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

TBS, pH 7.0 to 8.0, with 0.1% BSA

Contains

0.09% sodium azide

Storage conditions

4°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine, Dog, Horse, Rabbit, Guinea pig_10141, Pig, Golden hamster, Panda, Orangutan, Monkey, Gorilla and Chimpanzee

Target Information

STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13. (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation. STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 12S1644; IL-4 Stat; IL4 STAT; Signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; STAT; STAT, interleukin4-induced; STAT-6; transcription factor IL-4 STAT

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Gene Aliases: D12S1644; IL-4-STAT; STAT6; STAT6B; STAT6C

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UniProt ID: (Human) P42226

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Entrez Gene ID: (Human) 6778

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Function(s)
RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding signal transducer activity protein binding protein phosphatase binding identical protein binding
Process(es)
negative regulation of transcription from RNA polymerase II promoter T-helper 1 cell lineage commitment negative regulation of type 2 immune response transcription, DNA-templated regulation of transcription from RNA polymerase II promoter signal transduction positive regulation of type I interferon production mammary gland epithelial cell proliferation interleukin-4-mediated signaling pathway regulation of cell proliferation positive regulation of transcription from RNA polymerase II promoter positive regulation of isotype switching to IgE isotypes mammary gland morphogenesis cellular response to hydrogen peroxide cellular response to reactive nitrogen species
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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