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  • CD75 Antibodies

Invitrogen

ST6GAL1 Polyclonal Antibody

View all (22) CD75 antibodies

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Datasheet
Protocols
Questions & Answers

Cite ST6GAL1 Polyclonal Antibody

  • Antibody Testing Data (5)
ST6GAL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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ST6GAL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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ST6GAL1 Antibody (PA5-106647) in IHC (P)

Immunohistochemistry analysis of ST6GAL1 in human colorectal cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with ST6GAL1 polyclonal antibody (Product # PA5-106647) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ST6GAL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ST6GAL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ST6GAL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ST6GAL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ST6GAL1 Antibody in Western Blot (WB)

Product Details

PA5-106647

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human ST6GAL1(Accession P15907), corresponding to amino acid residues K177-T227.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2854315

Product Specific Information

Antibody detects endogenous levels of total ST6GAL1.

Target Information

The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein, which is normally found in the Golgi but which can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CDw75, and CD76. This protein is a member of glycosyltransferase family 29. Three transcript variants encoding two different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Alpha 2,6-ST 1; B-cell antigen CD75; beta galactoside alpha 2,6 sialyltransferase 1; Beta-galactoside alpha-2,6-sialyltransferase 1; CMP-N-acetylneuraminate beta-galactosamide alpha-2,6-sialyltransferase; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; Sialyltransferase 1; sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase); Sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase); Sialyltransferase 1 (beta-galactoside alpha-26-sialytransferase); ST6 beta-galactosamide alpha-2,6-sialyltranferase 1; ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; ST6Gal I; ST6GalI

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Gene Aliases: AW742324; SIAT1; St6gal; St6Gal-I; ST6GAL1; ST6GalI; ST6N

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UniProt ID: (Human) P15907, (Mouse) Q64685, (Rat) P13721

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Entrez Gene ID: (Human) 6480, (Mouse) 20440, (Rat) 25197

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Function(s)
beta-galactoside alpha-2,6-sialyltransferase activity protein binding sialyltransferase activity transferase activity transferase activity, transferring glycosyl groups
Process(es)
N-acetylneuraminate metabolic process protein glycosylation protein N-linked glycosylation via asparagine sialylation humoral immune response oligosaccharide metabolic process O-glycan processing positive regulation of mononuclear cell proliferation response to ethanol negative regulation of chemotaxis regulation of substrate adhesion-dependent cell spreading protein sialylation negative regulation of macrophage apoptotic process
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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