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  • SREBP2 Antibodies

Proteintech

SREBF2 Polyclonal Antibody

35 References
View all (18) SREBP2 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite SREBF2 Polyclonal Antibody

  • Antibody Testing Data (1)
SREBF2 Antibody in Western Blot (WB)
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SREBF2 Antibody in Western Blot (WB)
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SREBF2 Antibody (28212-1-AP) in WB

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SREBF2 Antibody in Western Blot (WB)

Product Details

28212-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:4,000
View 31 publications 31 publications

Immunohistochemistry (IHC)

-
View 3 publications 3 publications

Immunocytochemistry (ICC/IF)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SREBF2 Fusion Protein Ag28205

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

433 µg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Aliquoting is unnecessary for -20°C storage.

Target Information

This gene encodes a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: bHLHd2; Class D basic helix-loop-helix protein 2; SREBP-2; Sterol regulatory element-binding protein 2; Sterol regulatory element-binding transcription factor 2

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Gene Aliases: BHLHD2; SREBF2; SREBP-2; SREBP2

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UniProt ID: (Human) Q12772

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Entrez Gene ID: (Human) 6721

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Function(s)
C-8 sterol isomerase activity RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding protein binding protein C-terminus binding protein dimerization activity E-box binding
Process(es)
negative regulation of transcription from RNA polymerase II promoter transcription, DNA-templated lipid metabolic process cholesterol metabolic process cellular response to starvation positive regulation of cholesterol storage positive regulation of transcription from RNA polymerase II promoter response to low-density lipoprotein particle cellular response to laminar fluid shear stress regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter negative regulation of cholesterol efflux regulation of mitophagy positive regulation of protein targeting to mitochondrion regulation of cholesterol homeostasis
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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