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  • SRD5A2 Antibodies

Invitrogen

SRD5A2 Polyclonal Antibody

View all (9) SRD5A2 antibodies

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Datasheet
Protocols
Questions & Answers

Cite SRD5A2 Polyclonal Antibody

  • Antibody Testing Data (2)
SRD5A2 Antibody in Western Blot (WB)
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SRD5A2 Antibody in Western Blot (WB)
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SRD5A2 Antibody (PA5-113785) in WB

Western Blot of Monkey brain extract using a Polyclonal SRD5A2 Antibody (Product # PA5-113785). Lane 1: 50 µg monkey brain extract. Primary Antibody Dilution: 1:1,000. Secondary Antibody: Goat anti rabbit-HRP. Secondary Antibody Dilution: 1:10,000. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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SRD5A2 Antibody in Western Blot (WB)
SRD5A2 Antibody in Western Blot (WB)
SRD5A2 Polyclonal Antibody

Product Details

PA5-113785

Applications
Tested Dilution
Publications

Western Blot (WB)

0.2-1 µg/mL
-
Product Specifications

Species Reactivity

Human, Non-human primate

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the N terminal region of human SRD5A2 (aa 35-84).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2884300

Product Specific Information

Immunogen sequence: KHTESLKPAA TRLPARAAWF LQELPSFAVP AGILARQPLS LFGPPGTVLL

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Predicted homology: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 77%; Pig: 93%; Rabbit: 86%; Rat: 93%

Target Information

This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 3-oxo-5-alpha-steroid 4-dehydrogenase 2; 5 alpha-SR2; MGC138457; S5AR 2; SR type 2; Steroid 5-alpha-reductase 2; steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2); Type II 5-alpha reductase

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Gene Aliases: SRD5A2

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UniProt ID: (Human) P31213

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Entrez Gene ID: (Human) 6716

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Function(s)
3-oxo-5-alpha-steroid 4-dehydrogenase activity sterol 5-alpha reductase activity amide binding cholestenone 5-alpha-reductase activity
Process(es)
steroid biosynthetic process androgen biosynthetic process steroid catabolic process cell-cell signaling androgen metabolic process male gonad development biphenyl metabolic process dibenzo-p-dioxin metabolic process phthalate metabolic process hippocampus development hypothalamus development cell differentiation male genitalia development female genitalia development response to nutrient levels response to follicle-stimulating hormone response to testosterone response to drug response to peptide hormone response to steroid hormone oxidation-reduction process bone development
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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