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  • SPG20 Antibodies

Bethyl Laboratories

SPG20 Polyclonal Antibody

View all (12) SPG20 antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite SPG20 Polyclonal Antibody

  • Antibody Testing Data (2)
SPG20 Antibody in Western Blot (WB)
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SPG20 Antibody in Western Blot (WB)
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SPG20 Antibody (A305-375A) in WB

Detection of human SPG20 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-SPG20 antibody (Product # A305-375A) (lot A305-375A-1) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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SPG20 Antibody in Western Blot (WB)
SPG20 Antibody in Immunoprecipitation (IP)
SPG20 Polyclonal Antibody

Product Details

A305-375A

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000-1:10,000
-

Immunoprecipitation (IP)

2-10 µg/mg lysate
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Region between residue 350 to 400 of Human Spartin.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

phosphate/tris citrate, pH 7-8

Contains

0.09% sodium azide

Storage conditions

4°C

Shipping conditions

Wet ice

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Target Information

SPG20 is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Spartin; Spastic paraplegia 20 protein; Trans-activated by hepatitis C virus core protein 1

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Gene Aliases: KIAA0610; SPART; SPARTIN; SPG20; TAHCCP1

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UniProt ID: (Human) Q8N0X7

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Entrez Gene ID: (Human) 23111

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Function(s)
protein binding ubiquitin protein ligase binding
Process(es)
abscission negative regulation of BMP signaling pathway lipid particle organization negative regulation of collateral sprouting in absence of injury neuromuscular process cell division regulation of mitochondrial membrane potential adipose tissue development
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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