Invitrogen

SOX11 Recombinant Rabbit Monoclonal Antibody (SD203-08)

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Datasheet
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Datasheet
Protocols
Questions & Answers
SOX11 Recombinant Rabbit Monoclonal Antibody (SD203-08)

Product Details

MA5-32395

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

SD203-08

Immunogen

Synthetic peptide within Human SOX11 aa 1-50
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

TBS, pH 7.4, with 40% Glycerol, 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2809673

Product Specific Information

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Target Information

This intronless gene encodes a member of the SOX family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: SRY; SRY (sex-determining region Y)-box 11; SRY-box 11; SRY-box containing gene 11; SRY-related HMG-box gene 11; Transcription factor SOX-11

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Gene Aliases: 1110038H03Rik; 6230403H02Rik; AI836553; end1; MRD27; Sox-11; SOX11

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UniProt ID: (Human) P35716, (Mouse) Q7M6Y2, (Rat) P0C1G9

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Entrez Gene ID: (Human) 6664, (Mouse) 20666, (Rat) 84046

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Function(s)
transcription regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II transcription coactivator activity enhancer sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding translation factor activity, RNA binding DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding
Process(es)
negative regulation of transcription from RNA polymerase II promoter skeletal system development neural tube formation lens morphogenesis in camera-type eye outflow tract morphogenesis cardiac ventricle formation noradrenergic neuron differentiation transcription, DNA-templated regulation of transcription, DNA-templated transcription from RNA polymerase II promoter translation multicellular organism development nervous system development positive regulation of cell proliferation positive regulation of gene expression negative regulation of gene expression glial cell proliferation neural crest cell development spinal cord development glial cell development cell differentiation positive regulation of BMP signaling pathway positive regulation of hippo signaling skeletal muscle cell differentiation positive regulation of neuron differentiation positive regulation of osteoblast differentiation positive regulation of ossification positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of hormone secretion sympathetic nervous system development embryonic digestive tract morphogenesis embryonic skeletal system morphogenesis negative regulation of lymphocyte proliferation positive regulation of neurogenesis hard palate development soft palate development limb bud formation negative regulation of glial cell proliferation ventricular septum morphogenesis lung morphogenesis negative regulation of cell death neuroepithelial cell differentiation eyelid development in camera-type eye somite development cornea development in camera-type eye closure of optic fissure positive regulation of stem cell proliferation negative regulation of transcription regulatory region DNA binding positive regulation of lens epithelial cell proliferation kidney development oligodendrocyte development regulation of transforming growth factor beta receptor signaling pathway neuron differentiation signal transduction involved in cell cycle checkpoint cell proliferation
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