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Proteintech
SNAPIN Polyclonal Antibody
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Product Details
10055-1-AP
Species Reactivity
Published species
Host/Isotype
Class
Type
Immunogen
Conjugate
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Purification
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Product Specific Information
This antibody can recognize the 15-18 kDa (Monomer) and 30-36 kDa (Dimer) forms of SNAPIN.
Immunogen sequence: MAGAGSAAV SGAGTPVAGP TGRDLFAEGL LEFLRPAVQQ LDSHVHAVRE SQVELREQID NLATELCRIN EDQKVALDLD PYVKKLLNAR RRVVLVNNIL QNAQERLRRL NHSVAKETAR RRAMLDSGIY PPGSPGK (1-136 aa encoded by BC000761)
Target Information
The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: biogenesis of lysosomal organelles complex-1, subunit 7; Biogenesis of lysosome-related organelles complex 1 subunit 7; BLOC-1 subunit 7; SNAP-25-binding protein; SNAP-associated protein; SNARE associated protein snapin; SNARE-associated protein Snapin; synaptosomal-associated protein 25 binding protein; Synaptosomal-associated protein 25-binding protein; synaptosomal-associated protein, 25 kDa, binding protein
Gene Aliases: 25kDa; AA407989; AV026596; BLOC1S7; BLOS7; BORCS3; SNAP25BP; SNAPAP; SNAPIN
UniProt ID: (Human) O95295, (Mouse) Q9Z266, (Rat) P60192
Entrez Gene ID: (Human) 23557, (Mouse) 20615, (Rat) 295217
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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