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  • SMYD3 Antibodies

Proteintech

SMYD3 Polyclonal Antibody

5 References
View all (17) SMYD3 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite SMYD3 Polyclonal Antibody

  • Antibody Testing Data (15)
SMYD3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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SMYD3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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SMYD3 Antibody (12011-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using 12011-1-AP ( SMYD3 antibody) at dilution of 1:200 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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SMYD3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
SMYD3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
SMYD3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
SMYD3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
SMYD3 Antibody in Western Blot (WB)
SMYD3 Antibody in Western Blot (WB)
SMYD3 Antibody in Western Blot (WB)
SMYD3 Antibody in Western Blot (WB)
SMYD3 Antibody in Western Blot (WB)
SMYD3 Antibody in Western Blot (WB)
SMYD3 Antibody in Western Blot (WB)
SMYD3 Antibody in Western Blot (WB)
SMYD3 Antibody in Western Blot (WB)
SMYD3 Antibody in Western Blot (WB)
SMYD3 Antibody in Immunoprecipitation (IP)
SMYD3 Polyclonal Antibody

Product Details

12011-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
View 5 publications 5 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500
-

Immunoprecipitation (IP)

0.5-4.0 µg
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SMYD3 Fusion Protein Ag2624 (60-428 aa encoded by BC031010)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MRCSQCRVA KYCSAKCQKK AWPDHKRECK CLKSCKPRYP PDSVRLLGRV VFKLMDGAPS ESEKLYSFYD LESNINKLTE DRKEGLRQLV MTFQHFMREE IQDASQLPPA FDLFEAFAKV ICNSFTICNA EMQEVGVGLY PSISLLNHSC DPNCSIVFNG PHLLLRAVRD IEVGEELTIC YLDMLMTSEE RRKQLRDQYC FECDCFRCQT QDKDADMLTG DEQVWKEVQE SLKKIEELKA HWKWEQVLAM CQAIISSNSE RLPDINIYQL KVLDCAMDAC INLGLLEEAL FYGTRTMEPY RIFFPGSHPV RGVQVMKVGK LQLHQGMFPQ AMKNLRLAFD IMRVTHGREH SLIEDLILLL EECDANIRAS (60-428 aa encoded by BC031010)

Target Information

SMYD3 (histone-lysine N-methyltransferase) methylates Lys-4 of histone H3 and Lys-5 of histone H4. It induces di- and tri-methylation. SMYD3 plays an important role in transcriptional activation as a member of an RNA polymerase complex.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: bA74P14.1 (novel protein); Histone-lysine N-methyltransferase SMYD3; SET and MYND domain-containing protein 3; Zinc finger MYND domain-containing protein 1; zinc finger protein, subfamily 3A (MYND domain containing), 1; zinc finger, MYND domain containing 1

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Gene Aliases: 2410008A19Rik; bA74P14.1; KMT3E; SMYD3; ZMYND1; ZNFN3A1

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UniProt ID: (Human) Q9H7B4, (Mouse) Q9CWR2

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Entrez Gene ID: (Human) 64754, (Mouse) 69726, (Rat) 498295

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Function(s)
RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II core binding RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding histone-lysine N-methyltransferase activity metal ion binding protein binding methyltransferase activity transferase activity molecular_function
Process(es)
nucleosome assembly negative regulation of protein kinase activity myotube cell development chromatin modification methylation positive regulation of peptidyl-serine phosphorylation histone lysine methylation establishment of protein localization positive regulation of transcription from RNA polymerase II promoter cellular response to dexamethasone stimulus biological_process peptidyl-lysine methylation
It has to be done as per old AB suggested Products section.
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