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Invitrogen
SLC6A8 Polyclonal Antibody
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FIGURE: 1 / 2
SLC6A8 Antibody (PA5-110393) in WB
Product Details
PA5-110393
Species Reactivity
Published species
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Immunogen
Conjugate
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Product Specific Information
Immunogen sequence: VVYYEPLVYN NTYVYPWWGE AMGWAFALSS MLCVPLHLLG CLLRAKGTMA ERWQHLTQPI WGLHHLEYRA QDADVRGLTT LTPVSESSKV VVVESVM
Target Information
SLC6A8 (solute carrier family 6 member 8), also known as CT1 (creatine transporter 1), CRT or CRTR, is a 635 amino acid multi-pass plasma membrane protein that belongs to the sodium/neurotransporter (SNF) family. Expressed in a variety of tissues including kidney, skeletal muscle, heart, brain, prostate, testis and colon, SLC6A8 functions to transport creatine into and out of cells, specifically those found in brain and muscle tissue. Creatine, an organic acid, occurs naturally and is essential for supplying the energy needed for proper muscle and nerve function. Defects in the gene encoding SLC6A8 lead to cerebral creatine deficiency and are the cause of X-linked creatine deficiency syndrome, a rare disorder characterized by facial anomalies, seizures and mental retardation. Multiple isoforms of SLC6A8 exist due to alternative splicing events.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: creatine transporter 1; creatine transporter SLC6A8 variant D; creatine transporter, solute carrier family 6, member 8; CT1; MGC87396; Sodium- and chloride-dependent creatine transporter 1; solute carrier family 6 (neurotransmitter transporter), member 8; solute carrier family 6 (neurotransmitter transporter, creatine), member 8; Solute carrier family 6 member 8; solute carrier family 6, member 8
Gene Aliases: AA589632; CCDS1; Creat; CRT; CRTR; CT1; CTR5; SLC6A8
UniProt ID: (Human) P48029, (Mouse) Q8VBW1
Entrez Gene ID: (Human) 6535, (Mouse) 102857
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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