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  • Primary Antibodies ›
  • SLC26A3 Antibodies

Fabgennix

SLC26A3 Polyclonal Antibody, Biotin

View all (9) SLC26A3 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite SLC26A3 Polyclonal Antibody, Biotin

SLC26A3 Polyclonal Antibody, Biotin

Product Details

SLC26A3-BIOTIN

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500
-

ELISA (ELISA)

1:10,000
-

Immunoprecipitation (IP)

1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to amino acids within region 520-570 on human SCL26A3 protein.
View immunogen

Conjugate

Biotin Biotin Biotin

Form

Liquid

Concentration

0.5-1.5 mg/mL

Purification

Affinity chromatography

Storage buffer

proprietary buffer with 20% glycerol, 0.5% BSA

Contains

0.01% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Product Specific Information

Quantity: 100 µg IgG per vial

Target Information

SLC26A3 is a chloride/bicarbonate exchanger that is involved in absorption inside the colon. SLC26A3 helps mediate electrolyte and fluid absorption. The protein encoded by the SLC26A3 gene is a transmembrane glycoprotein that functions as a sulfate transporter, and it is localized to the mucosa. The chloride ions transported by SLC26A3 cross the cell membrane in exchange for biocarbonate ions. SLC26A3 is localized in the mucosa of the lower intestinal tract, specifically the apical membrane of the columnar epithelium and in some goblet cells. Diseases associated with SLC26A3 protein dysfunction include congenital chloride diarrhea and congenital secretory chloride diarrhea 1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Chloride anion exchanger; Down-regulated in adenoma; down-regulated in adenoma protein; Protein DRA; solute carrier family 26 (anion exchanger), member 3; Solute carrier family 26 member 3; solute carrier family 26, member 3

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Gene Aliases: 9030623B18Rik; 9130013M11Rik; AV376035; CLD; DRA; SLC26A3

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UniProt ID: (Human) P40879, (Mouse) Q9WVC8, (Rat) Q924C9

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Entrez Gene ID: (Human) 1811, (Mouse) 13487, (Rat) 114629

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Function(s)
transcription factor activity, sequence-specific DNA binding transcription cofactor activity transporter activity chloride channel activity inorganic anion exchanger activity protein binding secondary active sulfate transmembrane transporter activity bicarbonate transmembrane transporter activity chloride transmembrane transporter activity sulfate transmembrane transporter activity anion:anion antiporter activity oxalate transmembrane transporter activity antiporter activity
Process(es)
transport chloride transport sulfate transport bicarbonate transport sperm capacitation intracellular pH elevation transmembrane transport membrane hyperpolarization cellular response to cAMP anion transmembrane transport chloride transmembrane transport regulation of transcription, DNA-templated ion transport anion transport excretion oxalate transport regulation of membrane potential regulation of intracellular pH sulfate transmembrane transport
It has to be done as per old AB suggested Products section.
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