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  • Primary Antibodies ›
  • SKOR2 Antibodies

Invitrogen

SKOR2 Polyclonal Antibody

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite SKOR2 Polyclonal Antibody

  • Antibody Testing Data (4)
SKOR2 Antibody in Immunohistochemistry (IHC)
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SKOR2 Antibody in Immunohistochemistry (IHC)
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SKOR2 Antibody (PA5-61186) in IHC

Immunohistochemical staining of SKOR2 in mouse embryo E11 using SKOR2 Polyclonal Antibody (Product # PA5-61186) shows strong nuclear positivity in the developing cerebellum. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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SKOR2 Antibody in Immunohistochemistry (IHC)
SKOR2 Antibody in Immunohistochemistry (IHC)
SKOR2 Antibody in Immunohistochemistry (IHC)
SKOR2 Antibody in Immunohistochemistry (IHC)
SKOR2 Polyclonal Antibody

Product Details

PA5-61186

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1000
-
Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SKOR2. Recombinant protein control fragment (Product #RP-98298).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2647337

Product Specific Information

Immunogen sequence: MASSPLPGPN DILLASPSSA FQPDTLSQPR PGHANLKPNQ VGQVILYGIP IVS

Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

Target Information

Exhibits transcriptional repressor activity. Acts as a TGF-beta antagonist in the nervous system.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: functional Smad suppressor element on chromosome 18; Fussel-18 homolog; Ladybird homeobox corepressor 1-like protein; LBX1 corepressor 1-like protein; SKI family transcriptional corepressor 2; Transcriptional corepressor Corl2

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Gene Aliases: Corl2; EG664805; Fussel18; Gm7348; Skor2

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UniProt ID: (Mouse) A7M7C7

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Entrez Gene ID: (Mouse) 664805

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Function(s)
chromatin binding transcription corepressor activity histone deacetylase binding SMAD binding
Process(es)
negative regulation of transcription from RNA polymerase II promoter transcription, DNA-templated regulation of transcription, DNA-templated cerebellum morphogenesis cerebellar Purkinje cell differentiation regulation of cerebellar granule cell precursor proliferation negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of BMP signaling pathway positive regulation of smoothened signaling pathway cell development regulation of dendrite morphogenesis
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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