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  • SERPINE2 Antibodies

OriGene

SERPINE2 Monoclonal Antibody (OTI1G8), TrueMAB™

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Datasheet
Protocols
Questions & Answers

Cite SERPINE2 Monoclonal Antibody (OTI1G8), TrueMAB™

  • Antibody Testing Data (1)
SERPINE2 Antibody in Western Blot (WB)
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SERPINE2 Antibody in Western Blot (WB)
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SERPINE2 Antibody (CF504601) in WB

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SERPINE2 (RC204904, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SER. Positive lysates LY416795 (100 µg) and LC416795 (20 µg) can be purchased separately from OriGene. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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SERPINE2 Antibody in Western Blot (WB)
SERPINE2 Monoclonal Antibody (OTI1G8), TrueMAB™

Product Details

CF504601

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI1G8

Immunogen

Full length human recombinant protein of human SERPINE2 produced in HEK293T cell.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 8% trehalose

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

Target Information

This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: GDN; Glia derived nexin; Glia-derived nexin; glial-derived neurite promoting factor; P17; Peptidase inhibitor 7; PI-7; PN-1; Protease nexin 1; Protease nexin I; Serpin E2; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; SERPINE 2

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Gene Aliases: GDN; GDNPF; PI-7; PI7; PN-1; PN1; PNI; SERPINE2

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UniProt ID: (Human) P07093

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Entrez Gene ID: (Human) 5270

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Function(s)
serine-type endopeptidase inhibitor activity receptor binding protein binding glycosaminoglycan binding heparin binding
Process(es)
embryo implantation blood coagulation negative regulation of cell proliferation response to radiation negative regulation of plasminogen activation negative regulation of sodium ion transport negative regulation of endopeptidase activity negative regulation of protein processing positive regulation of neuron projection development negative regulation of phosphatidylinositol 3-kinase signaling cerebellar granular layer morphogenesis negative regulation of blood coagulation negative regulation of cell growth regulation of cell migration secretion by cell secretory granule organization negative regulation of protein catabolic process mating plug formation negative regulation of proteolysis negative regulation of smoothened signaling pathway regulation of timing of cell differentiation positive regulation of astrocyte differentiation detection of mechanical stimulus involved in sensory perception regulation of synaptic transmission, glutamatergic long-term synaptic potentiation innervation seminal vesicle epithelium development dense core granule biogenesis negative regulation of platelet aggregation
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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