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Proteintech
RYR1 Monoclonal Antibody (1B4E12)
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Product Details
66539-1-IG
Species Reactivity
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Type
Clone
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Conjugate
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Product Specific Information
Immunogen sequence: GELRDQQEQ VKEDMETKCF ICGIGSDYFD TTPHGFETHT LEEHNLANYM FFLMYLINKD ETEHTGQESY VWKMYQERCW DFFPAGDCFR KQYEDQLS (4942-5038 aa encoded by NM_000540)
Target Information
Ryanodine receptors have been shown to play critical roles in the intracellular Ca2+ signaling occurring during cell activation in muscle cells and non-muscled cells. Ryanodine receptor, ~500 kDa, can be isolated from a variety of cell types such as lymphocytes, macrophages, granulocytes, fibroblasts, epithelial, endothelial cells, skeletal muscles, cardiac muscle and brain tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: calcium release channel; central core disease of muscle; protein phosphatase 1, regulatory subunit 137; Ryanodine receptor; Ryanodine receptor 1; ryanodine receptor 1 (skeletal); RYR-1; sarcoplasmic reticulum calcium release channel; Skeletal muscle calcium release channel; Skeletal muscle ryanodine receptor; Skeletal muscle-type ryanodine receptor; Type 1 ryanodine receptor; type 1-like ryanodine receptor
Gene Aliases: AI528790; CCO; MHS; MHS1; PPP1R137; RYDR; RYR; RYR-1; RYR1; SKRR
UniProt ID: (Human) P21817, (Mouse) E9PZQ0
Entrez Gene ID: (Human) 6261, (Mouse) 20190
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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