Proteintech

RACK1, GNB2L1 Monoclonal Antibody (1E11A7), CoraLite® 594

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Datasheet
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Datasheet
Protocols
Questions & Answers
RACK1, GNB2L1 Monoclonal Antibody (1E11A7), CoraLite® 594

Product Details

CL59466940100UL

Applications
Tested Dilution
Publications

Immunocytochemistry (ICC/IF)

1:50-1:500
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

1E11A7

Conjugate

CoraLite® 594 CoraLite® 594 CoraLite® 594

Excitation/Emission Max

593/614 nm

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.5% BSA

Contains

0.05% ProClin 300

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles, store in dark

Shipping conditions

Wet ice

Target Information

RACK1 (receptor for activated C kinase 1) was identified through its binding to various PKC isoforms. Its main function is to recruit PKC and various other proteins to specific locations to form multiprotein complexes, mediating various signal pathways. RACK1 is required for VANGL2 membrane localization and for PTK2/FAK1 phosphorylation and dephosphorylation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Cell proliferation-inducing gene 21 protein; guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1; guanine nucleotide binding protein beta polypeptide 2-like 1; Guanine nucleotide-binding protein subunit beta-2-like 1; Guanine nucleotide-binding protein subunit beta-like protein 12.3; HLC-7; Human lung cancer oncogene 7 protein; lung cancer oncogene 7; OTTHUMP00000223870; OTTHUMP00000223891; OTTHUMP00000223893; OTTHUMP00000223900; OTTHUMP00000223901; OTTHUMP00000223902; OTTHUMP00000223930; OTTHUMP00000223931; proliferation-inducing gene 21; protein homologous to chicken B complex protein, guanine nucleotide binding; rack-1; Receptor for activated C kinase; Receptor of activated protein C kinase 1; receptor of activated protein kinase C 1; Small ribosomal subunit protein RACK1

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Gene Aliases: Gnb2-rs1; GNB2L1; H12.3; HLC-7; HLC7; PIG21; RACK1

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UniProt ID: (Human) P63244

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Entrez Gene ID: (Human) 10399

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Function(s)
protein kinase C binding receptor binding protein binding ion channel inhibitor activity cysteine-type endopeptidase activator activity involved in apoptotic process enzyme binding protein phosphatase binding protein tyrosine kinase inhibitor activity receptor tyrosine kinase binding protein complex scaffold signaling adaptor activity SH2 domain binding protein homodimerization activity poly(A) RNA binding cadherin binding involved in cell-cell adhesion
Process(es)
osteoblast differentiation positive regulation of protein phosphorylation apoptotic process activation of cysteine-type endopeptidase activity involved in apoptotic process cell cycle gastrulation negative regulation of gene expression regulation of tumor necrosis factor-mediated signaling pathway viral process negative regulation of translation negative regulation of Wnt signaling pathway negative regulation of cell growth positive regulation of cell migration positive regulation of cAMP catabolic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of protein homooligomerization regulation of protein localization negative regulation of peptidyl-serine phosphorylation positive regulation of Golgi to plasma membrane protein transport positive regulation of apoptotic process positive regulation of GTPase activity rhythmic process negative regulation of phagocytosis regulation of cell division positive regulation of cyclic-nucleotide phosphodiesterase activity regulation of cell cycle negative regulation of protein kinase B signaling positive regulation of mitochondrial depolarization negative regulation of protein tyrosine kinase activity cellular response to glucose stimulus cellular response to growth factor stimulus cell-cell adhesion negative regulation of endoplasmic reticulum unfolded protein response negative regulation of hydrogen peroxide-induced neuron death regulation of establishment of cell polarity positive regulation of ceramide biosynthetic process positive regulation of gastrulation positive regulation of intrinsic apoptotic signaling pathway
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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