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Invitrogen
RACGAP1 Polyclonal Antibody
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Product Details
PA5-29698
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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RRID
Product Specific Information
Recommended positive controls: 293T, A431, Jurkat, Raji.
Predicted reactivity: Mouse (81%), Rat (82%), Rhesus Monkey (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
RAC, a small GTPase in the ras family, regulates the formation of membrane ruffles, lamellipodia and filopodia. It is involved in cytoskeletal actin organization and transformation. The p21 activated kinases (PAKs) are direct targets of active Rac and Cdc42 which can induce the assembly of polarized cytoskeletal structures when expressed in fibroblasts. RAC1 and RAC2 are also essential components of NADPH oxidase, the enzyme responsible for generating free radicals.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: AKT; CYK4; GAP; ID; Male germ cell RacGap; MGC99656; MgcRacGAP; PKB; PKB-ALPHA; PRKBA; protein CYK4 homolg; Protein CYK4 homolog; RAC; Rac GTPase-activating protein 1; RAC-ALPHA
Gene Aliases: CYK4; HsCYK-4; ID-GAP; KIAA1478; MGCRACGAP; RACGAP1
UniProt ID: (Human) Q9H0H5
Entrez Gene ID: (Human) 29127
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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