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  • Primary Antibodies ›
  • RAC2 Antibodies

Abnova

RAC2 Monoclonal Antibody (3B10-2D9)

View all (11) RAC2 antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite RAC2 Monoclonal Antibody (3B10-2D9)

RAC2 Monoclonal Antibody (3B10-2D9)

Product Details

H00005880-M01A

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgM, kappa

Class

Monoclonal

Type

Antibody

Clone

3B10-2D9

Immunogen

RAC2 (AAH01485.1, 1 a.a. approximately 192 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage buffer

ascites

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDSKP VNLGLWDTAG QEDYDRLRPL SYPQTDVFLI CFSLVSPASY ENVRAKWFPE VRHHCPSTPI ILVGTKLDLR DDKDTIEKLK EKKLAPITYP QGLALAKEID SVKYLECSAL TQRGLKTVFD EAIRAVLCPQ PTRQQKRACS LL

Target Information

RAC, a small GTPase in the ras family, regulates the formation of membrane ruffles, lamellipodia and filopodia. It is involved in cytoskeletal actin organization and transformation. The p21 activated kinases (PAKs) are direct targets of active Rac and Cdc42 which can induce the assembly of polarized cytoskeletal structures when expressed in fibroblasts. RAC1 and RAC2 are also essential components of NADPH oxidase, the enzyme responsible for generating free radicals.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: GX; p21-Rac2; Ras-related C3 botulinum toxin substrate 2; Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2); Small G protein

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Gene Aliases: EN-7; Gx; HSPC022; p21-Rac2; RAC2

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UniProt ID: (Human) P15153

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Entrez Gene ID: (Human) 5880

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Function(s)
GTPase activity GTP binding protein kinase regulator activity
Process(es)
chemotaxis actin filament organization signal transduction G-protein coupled receptor signaling pathway small GTPase mediated signal transduction positive regulation of cell proliferation regulation of hydrogen peroxide metabolic process positive regulation of lamellipodium assembly regulation of cell-substrate adhesion cell projection assembly platelet activation regulation of T cell proliferation regulation of mast cell degranulation bone resorption regulation of protein kinase activity regulation of small GTPase mediated signal transduction regulation of respiratory burst regulation of mast cell chemotaxis lymphocyte aggregation positive regulation of neutrophil chemotaxis regulation of neutrophil migration positive regulation of protein targeting to mitochondrion
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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