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Invitrogen
RAB9 Recombinant Rabbit Monoclonal Antibody (SR45-05)
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FIGURE: 1 / 9
RAB9 Antibody (MA5-31997) in ICC/IF
Product Details
MA5-31997
Species Reactivity
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Conjugate
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Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
Rab proteins are a family of Ras-like GTPases involved in intracellular compartment protein transport. Different members of the 40+ member rab family are responsible for docking and fusion of transport vesicles between different compartments within the cell. Rab 9 is required for trafficking mannose 6-phosphate receptor between the late endosome to trans-Golgi network (TGN). By facilitating receptor transport, rab 9 enables cells to efficiently recycle important cellular trafficking components. It is functionally necessary for rab 9, like other rab family members, to be prenylated by two 20-carbon geranylgeranyl groups at the C-terminus. Most prenylated rab 9 is membrane bound, however, 10-20% of the cellular pool of rab 9 is bound to GDP dissociation inhibitor-alpha (GDI-alpha) in the cytosol. GDI recycles prenylated, GDP bound rab 9 from their fusion targets back to their membranes of origin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: rab-9A; RAB9, member RAS oncogene family; RAB9-like protein; Ras-related protein Rab-9A; SID 99
Gene Aliases: 2410064E05Rik; AI195561; RAB9; RAB9A; Sid6061p; Sid99
UniProt ID: (Human) P51151, (Mouse) Q9R0M6, (Rat) Q99P75
Entrez Gene ID: (Human) 9367, (Mouse) 56382, (Rat) 84589
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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