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  • proANP Antibodies

Invitrogen

ProANP Monoclonal Antibody (C6)

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite ProANP Monoclonal Antibody (C6)

  • Antibody Testing Data (1)
ProANP Antibody in Western Blot (WB)
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ProANP Antibody in Western Blot (WB)
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ProANP Antibody (MA5-51085) in WB

Western blot analysis of ProANP in Rat Heart lysate. Samples were incubated with ProANP monoclonal antibody (Product # MA5-51085) using a dilution of 0.2 µg/mL followed by HRP-Linked Caprine Anti-Mouse IgG secondary antibody at a dilution of 0.2 µg/mL. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ProANP Antibody in Western Blot (WB)
ProANP Monoclonal Antibody (C6)

Product Details

MA5-51085

Applications
Tested Dilution
Publications

Western Blot (WB)

0.2-2 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

2-20 µg/mL
-

Immunocytochemistry (ICC/IF)

2-20 µg/mL
-
Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

C6

Immunogen

Recombinant Human NT-ProANP protein, Ala25-Arg123 (Accession #P01160)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.05% Proclin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_3093428

Target Information

Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ANPRC; atrial natriuretic factor; Atrial natriuretic factor prohormone; atrial natriuretic peptide; Atrial natriuretic peptide prohormone; Atrial natriuretic peptide receptor 3; Atriopeptigen; atriopeptin; Cardiodilatin; cardiodilatin-related peptide; cardionatrin; CDD; Natriuretic peptide precursor A (pronatriodilatin, also Anf, Pnd); natriuretic peptide precursor A variant 1; natriuretic peptide precursor type A; Natriuretic peptides A; NPR3; preproANF; preproANP; preproCDD-ANF; prepronatriodilatin; proANF

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Gene Aliases: ANF; ANP; ATFB6; ATRST2; CDD; CDD-ANF; CDP; NPPA; PND; RATANF

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UniProt ID: (Human) P01160, (Rat) P01161

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Entrez Gene ID: (Human) 4878, (Rat) 24602

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Function(s)
receptor binding neuropeptide hormone activity protein binding peptide hormone receptor binding neuropeptide receptor binding hormone activity
Process(es)
response to hypoxia negative regulation of systemic arterial blood pressure cGMP biosynthetic process transcription initiation from RNA polymerase II promoter receptor guanylyl cyclase signaling pathway neuropeptide signaling pathway female pregnancy regulation of blood pressure positive regulation of heart rate cardiac muscle hypertrophy in response to stress negative regulation of cell growth response to insulin response to muscle stretch cellular protein metabolic process regulation of blood vessel size regulation of atrial cardiac muscle cell membrane repolarization positive regulation of cardiac muscle contraction cell growth involved in cardiac muscle cell development cellular response to mechanical stimulus regulation of high voltage-gated calcium channel activity positive regulation of delayed rectifier potassium channel activity regulation of calcium ion transmembrane transport via high voltage-gated calcium channel positive regulation of potassium ion export across plasma membrane regulation of cardiac conduction negative regulation of collecting lymphatic vessel constriction heart development regulation of body fluid levels multicellular organismal water homeostasis
It has to be done as per old AB suggested Products section.
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