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Phospho-delta 1 Catenin (Tyr280) Polyclonal Antibody

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite Phospho-delta 1 Catenin (Tyr280) Polyclonal Antibody

  • Antibody Testing Data (1)
Phospho-delta 1 Catenin (Tyr280) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Phospho-delta 1 Catenin (Tyr280) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Phospho-delta 1 Catenin (Tyr280) Antibody (BS-14262R) in IHC (P)

Paraformaldehyde-fixed, paraffin embedded Mouse brain; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with delta 1 Catenin (Tyr280) Polyclonal Antibody, Unconjugated (bs-14262R) at 1:400 overnight at 4°C, DAB staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Phospho-delta 1 Catenin (Tyr280) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Phospho-delta 1 Catenin (Tyr280) Polyclonal Antibody

Product Details

BS-14262R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300-1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:400
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthesised phosphopeptide derived from human delta 1 Catenin around the phosphorylation site of Tyr280.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Delta 1 Catenin is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Cadherin-associated Src substrate; Cadherin-associated Src substrate (CAS); CAS; Catenin (cadherin associated protein) delta 1; catenin (cadherin-associated protein), delta 1; Catenin delta-1; catenin src; p120 catenin; P120 CTN; P120 p120; P120 P120CTN; p120(cas); p120(ctn); p120-catenin

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Gene Aliases: AA409437; AU019353; CAS; Catns; CTNND; CTNND1; KIAA0384; mKIAA0384; P120; p120(CAS); p120(CTN); P120CAS; P120CTN

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UniProt ID: (Human) O60716, (Mouse) P30999

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Entrez Gene ID: (Human) 1500, (Mouse) 12388, (Rat) 311163

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Function(s)
receptor binding protein binding protein kinase binding cadherin binding cadherin binding involved in cell-cell adhesion protein phosphatase binding protein domain specific binding cell adhesion molecule binding
Process(es)
morphogenesis of a polarized epithelium transcription, DNA-templated regulation of transcription, DNA-templated cell adhesion salivary gland morphogenesis Wnt signaling pathway single organismal cell-cell adhesion keratinocyte differentiation epithelial cell differentiation involved in salivary gland development negative regulation of canonical Wnt signaling pathway brain development adherens junction organization
It has to be done as per old AB suggested Products section.
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