Phospho-c-Abl (Tyr245) Monoclonal Antibody (S.44.4)

magnesium ion binding DNA binding actin monomer binding nicotinate-nucleotide adenylyltransferase activity protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein kinase C binding receptor binding protein binding ATP binding protein C-terminus binding SH3 domain binding syntaxin binding manganese ion binding actin filament binding mitogen-activated protein kinase binding proline-rich region binding nucleotide binding kinase activity transferase activity transferase activity, transferring phosphorus-containing groups protein kinase binding protein domain specific binding metal ion binding delta-catenin binding

B-1 B cell homeostasis positive regulation of protein phosphorylation B cell proliferation involved in immune response transitional one stage B cell differentiation mismatch repair regulation of transcription, DNA-templated cellular protein modification process autophagy cellular response to DNA damage stimulus DNA damage induced protein phosphorylation response to oxidative stress cell cycle arrest mitotic nuclear division epidermal growth factor receptor signaling pathway positive regulation of cytosolic calcium ion concentration intrinsic apoptotic signaling pathway in response to DNA damage regulation of autophagy peptidyl-tyrosine phosphorylation cerebellum morphogenesis negative regulation of cell-cell adhesion microspike assembly actin cytoskeleton organization regulation of endocytosis regulation of cell adhesion negative regulation of BMP signaling pathway regulation of axon extension regulation of microtubule polymerization regulation of actin cytoskeleton organization positive regulation of osteoblast proliferation substrate adhesion-dependent cell spreading cellular response to oxidative stress platelet-derived growth factor receptor-beta signaling pathway peptidyl-tyrosine autophosphorylation Fc-gamma receptor signaling pathway involved in phagocytosis regulation of cell proliferation signal transduction in response to DNA damage positive regulation of apoptotic process positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of I-kappaB kinase/NF-kappaB signaling innate immune response establishment of protein localization negative regulation of mitotic cell cycle positive regulation of mitotic cell cycle alpha-beta T cell differentiation protein autophosphorylation spleen development thymus development collateral sprouting positive regulation of peptidyl-tyrosine phosphorylation activated T cell proliferation B cell receptor signaling pathway neuromuscular process controlling balance positive regulation of muscle cell differentiation positive regulation of release of sequestered calcium ion into cytosol positive regulation of oxidoreductase activity negative regulation of ubiquitin-protein transferase activity mitochondrial depolarization Bergmann glial cell differentiation cellular response to hydrogen peroxide negative regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade cellular response to lipopolysaccharide negative regulation of protein serine/threonine kinase activity actin filament branching positive regulation of interleukin-2 secretion negative regulation of phospholipase C activity positive regulation of neuron death positive regulation of interferon-gamma secretion regulation of extracellular matrix organization cellular response to dopamine positive regulation of microtubule binding positive regulation of actin filament binding activation of protein kinase C activity positive regulation of Wnt signaling pathway, planar cell polarity pathway regulation of cell motility regulation of actin cytoskeleton reorganization negative regulation of endothelial cell apoptotic process negative regulation of cellular senescence regulation of response to DNA damage stimulus DNA repair protein phosphorylation endocytosis phagocytosis apoptotic process cell adhesion phosphorylation cell migration B cell proliferation platelet-derived growth factor receptor signaling pathway regulation of cell cycle regulation of cellular senescence