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  • GAP43 Antibodies

Invitrogen

Phospho-GAP43 (Ser41) Polyclonal Antibody

View all (45) GAP43 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite Phospho-GAP43 (Ser41) Polyclonal Antibody

  • Antibody Testing Data (2)
Phospho-GAP43 (Ser41) Antibody in Immunocytochemistry (ICC/IF)
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Phospho-GAP43 (Ser41) Antibody in Immunocytochemistry (ICC/IF)
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Phospho-GAP43 (Ser41) Antibody (PA5-114577) in ICC/IF

Immunocytochemistry analysis of Phospho-GAP43 (Ser41) in HeLa cells (heat shock treatment). Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-114577). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjug... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Phospho-GAP43 (Ser41) Antibody in Immunocytochemistry (ICC/IF)
Phospho-GAP43 (Ser41) Antibody in Western Blot (WB)
Phospho-GAP43 (Ser41) Polyclonal Antibody

Product Details

PA5-114577

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-
Product Specifications

Species Reactivity

Human, Mouse, Non-human primate, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human GAP43 around the phosphorylation site of Ser41.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2899213

Product Specific Information

Antibody detects endogenous levels of GAP43 only when phosphorylated at Ser41.

Target Information

GAP43 (Neuromodulin) is associated with nerve growth. GAP43 is expressed by developing and regenerating neurons, and to a lesser extent reactive glial cells. It is a major component of the motile "growth cones" that form the tips of elongating axons. GAP43 also plays a role in axonal and dendritic filopodia induction.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Axonal membrane protein GAP-43; brain abundant, membrane attached signal protein 2; Calmodulin-binding protein P-57; growth accentuating protein 43; Growth-associated protein 43; MGC156666; nerve growth-related peptide GAP43; Neural phosphoprotein B-50; Neuromodulin; neuron growth-associated protein 43; neuron protein F1; pp46; Protein F1

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Gene Aliases: B-50; Basp2; GAP-43; GAP43; PP46

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UniProt ID: (Human) P17677, (Rat) P07936, (Mouse) P06837

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Entrez Gene ID: (Human) 2596, (Rat) 29423, (Mouse) 14432

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Function(s)
phosphatidylserine binding protein binding calmodulin binding lysophosphatidic acid binding phosphatidylinositol phosphate binding
Process(es)
nervous system development axon guidance glial cell differentiation axon choice point recognition regulation of growth tissue regeneration cell fate commitment regulation of filopodium assembly axon development multicellular organism development cell differentiation protein kinase C-activating G-protein coupled receptor signaling pathway response to wounding
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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