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Invitrogen
Phospho-ETS1 (Thr38) Polyclonal Antibody
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FIGURE: 1 / 4
Phospho-ETS1 (Thr38) Antibody (44-1104G) in WB
Product Details
44-1104G
Species Reactivity
Published species
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
RRID
Target Information
ETS1 (c-Ets-1; v-ets erythroblastosis virus E26 oncogene homlog 1 (avian); ETS-1; EWSR2; p54), a 441 A. A protein, is a member of DNA-binding ETS protein family. It is a multifunctional protein consisting of an N-terminal pointed domain, a central transactivation domain and 2 auto inhibitory domains flanked on both sides of conserved C-terminal Ets domain. It interacts with factors including PEBP2alphaA, p300/CBP and mediates transactivation of Osteopontin, Presenilin-1, Stromelysin and Collagenase. It is activated by Ras/MAPK signaling and its expression is up-regulated in resting T-cells. Its activity is modulated by various factors including AP-1, Sp-1, c-myb and MafB. Sp100 activates ETS1 in nuclear bodies. It interacts with EAP1/Daxx and causes repression of MMP1 and BCL2 transactivation. It interacts with STAT6 and modulates Socs-1 expression induced by IL-4. It interacts with GATA3 and positively regulates Tax-1 dependent IL-5 expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1; avian erythroblastosis virus E26 oncogene 1; c-ets-1 oncogene; Ets avian erythroblastosis virus E2 oncogene homolog 1 (tumor progression locus 1); ets protein; Ets-1Delta(III-VI); FLJ10768; p54; p54 transcription factor; Protein C-ets-1; TNFAIP3 interacting protein 1; Transforming protein p54/c-ets-1; Transforming protein p68/c-ets-1; tumor progression locus 1; v-ets avian erythroblastosis virus E2 oncogene homolog 1; v-ets avian erythroblastosis virus E26 oncogene homolog 1; v-ets erythroblastosis virus E26 oncogene homolog 1; virion-associated nuclear-shuttling protein
Gene Aliases: AI196000; AI448617; c-ets-1; c-ets1; D230050P06; ETS-1; ETS-1A; ETS-1B; ETS1; Etsoncb; EWSR2; p54; TNIP1; Tpl1
UniProt ID: (Chicken) P13474, (Human) P14921, (Rat) P41156, (Mouse) P27577
Entrez Gene ID: (Chicken) 396235, (Human) 2113, (Rabbit) 100009373, (Rat) 24356, (Mouse) 23871
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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