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Bioss
Phospho-DARPP32 (Thr34) Polyclonal Antibody
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FIGURE: 1 / 1
Phospho-DARPP32 (Thr34) Antibody (BS-3118R) in WB
Product Details
BS-3118R
Species Reactivity
Host/Isotype
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Type
Immunogen
Conjugate
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Target Information
DARPP-32 is a dopamine (DA) and AMP-regugated ~32 kDa phosphoprotein that is associated with dopaminoceptive neurons. The protein inhibits Protein Phosphatase I when it is phosphorylated on Thr34. In contrast, when DARPP-32 is phosphorylated on Thr75 the protein acts as an inhibitor of PKA. Phosphorylation of DARPP-32 is thought to play a critical role in the regugation of dopaminergic neurotransmission. In addition, the activity of DARPP-32 is also thought to play important roles in the actions of alcohol, caffeine and Prozac®.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: DARPP-32; dopamine and cAMP-regulated neuronal phosphoprotein 32; Dopamine- and cAMP-regulated neuronal phosphoprotein; FLJ20940; IPPD; OTTHUMP00000164275; OTTHUMP00000164276; PPR1B; protein pho; Protein phosphatase 1 regulatory subunit 1B
Gene Aliases: AU040756; DARPP-32; DARPP32; PPP1R1B
UniProt ID: (Human) Q9UD71, (Mouse) Q60829
Entrez Gene ID: (Human) 84152, (Mouse) 19049
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