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Parathyroid Hormone (PTH) (N- and C-Terminal) Monoclonal Antibody (3H9, PTH/1175)

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Cite Parathyroid Hormone (PTH) (N- and C-Terminal) Monoclonal Antibody (3H9, PTH/1175)

  • Antibody Testing Data (1)
Parathyroid Hormone (PTH) (N- and C-Terminal) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Parathyroid Hormone (PTH) (N- and C-Terminal) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Parathyroid Hormone (PTH) (N- and C-Terminal) Antibody (5741-MSM6-P0) in IHC (P)

Formalin-fixed, paraffin-embedded human Parathyroid stained with PTH Monoclonal Antibody (3H9 +PTH/1175). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Parathyroid Hormone (PTH) (N- and C-Terminal) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Parathyroid Hormone (PTH) (N- and C-Terminal) Monoclonal Antibody (3H9, PTH/1175)

Product Details

5741-MSM6-P0

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent
-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1-2 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

3H9, PTH/1175

Immunogen

A synthetic peptide around aa 1-34 of human mature-PTH-polypeptide. (3H9). A recombinant fragment around aa 32-115 of human mature PTH-polypeptide.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4°C, do not freeze

Shipping conditions

Wet ice

Product Specific Information

Predicted to react with Mouse, Rat, Rabbit, Cow, Dog, Pig, Deer, Orangutan

Target Information

This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Parathormone; Parathyrin; Parathyroid hormone; parathyroid hormone 1; prepro-PTH; preproparathyroid hormone; PTH

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Gene Aliases: PTH; PTH1

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UniProt ID: (Human) P01270

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Entrez Gene ID: (Human) 5741

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Function(s)
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding hormone activity parathyroid hormone receptor binding type 1 parathyroid hormone receptor binding peptide hormone receptor binding
Process(es)
negative regulation of transcription from RNA polymerase II promoter skeletal system development cellular calcium ion homeostasis G-protein coupled receptor signaling pathway adenylate cyclase-activating G-protein coupled receptor signaling pathway Rho protein signal transduction cell-cell signaling hormone-mediated apoptotic signaling pathway positive regulation of signal transduction response to lead ion regulation of gene expression positive regulation of bone mineralization positive regulation of cAMP biosynthetic process response to vitamin D cellular macromolecule biosynthetic process response to drug bone resorption response to ethanol positive regulation of glycogen biosynthetic process positive regulation of transcription from RNA polymerase II promoter cAMP metabolic process positive regulation of glucose import response to cadmium ion homeostasis of number of cells within a tissue response to parathyroid hormone response to fibroblast growth factor positive regulation of cell proliferation in bone marrow negative regulation of apoptotic process in bone marrow positive regulation of osteoclast proliferation
It has to be done as per old AB suggested Products section.
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