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Proteintech
PURA Polyclonal Antibody
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Product Details
17733-1-AP
Species Reactivity
Published species
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Immunogen sequence: MADRDSGSE QGGAALGSGG SLGHPGSGSG SGGGGGGGGG GGGSGGGGGG APGGLQHETQ ELASKRVDIR NKRFYLDVKQ NAKGRFLKIA EVGAGGNKSR LTLSMSVAVE FRDYLGDFIE HYAQLGPSQP PDLAQAQDEP RRALKSEFLV RENRKYYMDL KENQRGRFLR IRQTVNRGPG LGSTQGQTIA LPAQGLIEFR DALAKLIDDY GVEEEPAELP EGTSLTVDNK RFFFDVGSNK YGVFMRVSEV KPTYRNSITV PYKVWAKFGH TFCKYSEEMK KIQEKQREKR AACEQLHQQQ QQQQEETAAA TLLLQGEEEG EED (1-322 aa encoded by BC036087)
Target Information
This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Pur alpha; pura {ECO:0000250|UniProtKB:P42669}; purine rich element binding protein A; purine-rich element binding protein A; Purine-rich single-stranded DNA-binding protein alpha; purine-rich single-stranded DNA-binding protein alpha {ECO:0000250|UniProtKB:P42669}; Transcriptional activator protein Pur-alpha; transcriptional activator protein Pur-alpha {ECO:0000250|UniProtKB:P42669}
Gene Aliases: CAGER-1; MRD31; PUR-ALPHA; PUR1; PURA; PURALPHA; ssCRE-BP
UniProt ID: (Human) Q00577, (Mouse) P42669
Entrez Gene ID: (Human) 5813, (Mouse) 19290, (Rat) 307498
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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