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  • Primary Antibodies ›
  • PTCH2 Antibodies

Invitrogen

PTCH2 Polyclonal Antibody

View all (10) PTCH2 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite PTCH2 Polyclonal Antibody

  • Antibody Testing Data (1)
PTCH2 Antibody in Western Blot (WB)
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PTCH2 Antibody in Western Blot (WB)
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PTCH2 Antibody (PA5-95068) in WB

Western blot analysis of PTCH2 in HeLa cell lysate. Samples were incubated with PTCH2 polyclonal antibody (Product # PA5-95068). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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PTCH2 Antibody in Western Blot (WB)
PTCH2 Polyclonal Antibody

Product Details

PA5-95068

Applications
Tested Dilution
Publications

Western Blot (WB)

0.1-0.5 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human PTCH2 (885-901aa WLHDKYDTTGENLRIPP).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

500 µg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 5mg BSA

Contains

0.05mg sodium azide, 0.05mg thimerosal

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2806874

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Positive Control - WB: HELA Cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Information

Mutations of the human Patched tumor suppressor gene (PTCH) have been identified in individuals with the nevoid basal cell carcinoma syndrome (NBCCS) as well as in sporadic basal cell carcinomas and medulloblastomas. PTCH2 has a frameshift mutation resulting in a truncated PTCH2 protein.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: patched homolog 2; Protein patched homolog 2; PTC2; RP11-269F19.8

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Gene Aliases: PTC2; PTCH2; UNQ560/PRO1121/PRO57079

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UniProt ID: (Human) Q9Y6C5, (Mouse) O35595

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Entrez Gene ID: (Human) 8643, (Mouse) 19207

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Function(s)
smoothened binding hedgehog receptor activity hedgehog family protein binding
Process(es)
cell fate determination epidermis development epidermal cell fate specification hair cycle skin development positive regulation of epidermal cell differentiation signal transduction negative regulation of smoothened signaling pathway
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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