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  • PSMB4 Antibodies

Proteintech

PSMB4 Polyclonal Antibody

5 References
View all (25) PSMB4 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite PSMB4 Polyclonal Antibody

  • Antibody Testing Data (10)
PSMB4 Antibody in Immunocytochemistry (ICC/IF)
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PSMB4 Antibody in Immunocytochemistry (ICC/IF)
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FIGURE: 1 / 10

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PSMB4 Antibody (11029-1-AP) in ICC/IF

Immunofluorescent analysis of MCF-7 cells, using PSMB4 antibody 11029-1-AP at 1:50 dilution and FITC-labeled donkey anti-rabbit IGG (green). Blue pseudocolor = DAPI (fluorescent DNA dye). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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PSMB4 Antibody in Immunocytochemistry (ICC/IF)
PSMB4 Antibody in Immunocytochemistry (ICC/IF)
PSMB4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PSMB4 Antibody in Western Blot (WB)
PSMB4 Antibody in Western Blot (WB)
PSMB4 Antibody in Western Blot (WB)
PSMB4 Antibody in Western Blot (WB)
PSMB4 Antibody in Western Blot (WB)
PSMB4 Antibody in Western Blot (WB)
PSMB4 Antibody in Western Blot (WB)
PSMB4 Polyclonal Antibody

Product Details

11029-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
View 3 publications 3 publications

Immunohistochemistry (IHC)

-
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200
-

Immunocytochemistry (ICC/IF)

1:20-1:200
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Non-human primate, Pig

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PSMB4 Fusion Protein Ag1500 (1-264 aa encoded by BC010088)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MEAFLGSRS GLWAGGPAPG QFYRIPSTPD SFMDPASALY RGPITRTQNP MVTGTSVLGV KFEGGVVIAA DMLGSYGSLA RFRNISRIMR VNNSTMLGAS GDYADFQYLK QVLGQMVIDE ELLGDGHSYS PRAIHSWLTR AMYSRRSKMN PLWNTMVIGG YADGESFLGY VDMLGVAYEA PSLATGYGAY LAQPLLREVL EKQPVLSQTE ARDLVERCMR VLYYRDARSY NRFQTATVTE KGVEIEGPLS TETNWDIAHM ISGFE (1-264 aa encoded by BC010088)

Target Information

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: 26 kDa prosomal protein; beta-7; HsBPROS26; HsN3; Low molecular mass protein 3; Macropain beta chain; Multicatalytic endopeptidase complex beta chain; proteasome (prosome, macropain) subunit, beta type, 4; Proteasome beta chain; Proteasome chain 3; Proteasome subunit beta type-4; Proteasome subunit beta-7; proteasome subunit HsN3; proteasome subunit, beta type, 4; testis tissue sperm-binding protein Li 79P

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Gene Aliases: HN3; HsN3; Lmp3; PROS-26; Pros-27; PROS26; PSMB4

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UniProt ID: (Human) P28070, (Mouse) P99026

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Entrez Gene ID: (Human) 5692, (Mouse) 19172

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Function(s)
lipopolysaccharide binding threonine-type endopeptidase activity protein binding endopeptidase activity peptidase activity hydrolase activity
Process(es)
MAPK cascade protein polyubiquitination stimulatory C-type lectin receptor signaling pathway antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent negative regulation of inflammatory response to antigenic stimulus regulation of cellular amino acid metabolic process viral process anaphase-promoting complex-dependent catabolic process tumor necrosis factor-mediated signaling pathway NIK/NF-kappaB signaling Fc-epsilon receptor signaling pathway proteasome-mediated ubiquitin-dependent protein catabolic process regulation of mRNA stability T cell receptor signaling pathway negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition Wnt signaling pathway, planar cell polarity pathway negative regulation of canonical Wnt signaling pathway positive regulation of canonical Wnt signaling pathway proteolysis proteasomal ubiquitin-independent protein catabolic process proteolysis involved in cellular protein catabolic process
It has to be done as per old AB suggested Products section.
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