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  • PSMA2 Antibodies

Invitrogen

PSMA2 Polyclonal Antibody

View all (31) PSMA2 antibodies

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Datasheet
Protocols
Questions & Answers

Cite PSMA2 Polyclonal Antibody

  • Antibody Testing Data (1)
PSMA2 Antibody in Western Blot (WB)
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PSMA2 Antibody in Western Blot (WB)
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PSMA2 Antibody (PA5-89287) in WB

Western blot analysis of PSMA2 in extracts of various cell lines. Samples were incubated with PSMA2 Polyclonal antibody (Product # PA5-89287) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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PSMA2 Antibody in Western Blot (WB)
PSMA2 Polyclonal Antibody

Product Details

PA5-89287

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-234 of human PSMA2 (NP_0027781)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.7 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805469

Product Specific Information

Immunogen sequence: MAERGYSFSL TTFSPSGKLV QIEYALAAVA GGAPSVGIKA ANGVVLATEK KQKSILYDER SVHKVEPITK HIGLVYSGMG PDYRVLVHRA RKLAQQYYLV YQEPIPTAQL VQRVASVMQE YTQSGGVRPF GVSLLICGWN EGRPYLFQSD PSGAYFAWKA TAMGKNYVNG KTFLEKRYNE DLELEDAIHT AILTLKESFE GQMTEDNIEV GICNEAGFRR LTPTEVKDYL AAIA; Positive Samples: 293T, Jurkat, U-251MG, HeLa, NIH/3T3, 22Rv1, Raji, Mouse brain, Mouse kidney; Cellular Location: Cytoplasm, Nucleus, P-body

Target Information

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: alpha-2; Macropain subunit C3; Multicatalytic endopeptidase complex subunit C3; OTTHUMP00000207364; OTTHUMP00000207366; proteasome (prosome, macropain) subunit, alpha type, 2; Proteasome component C3; Proteasome subunit alpha type-2; Proteasome subunit alpha-2; proteasome subunit HC3; PSMA 2

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Gene Aliases: HC3; Lmpc3; MU; PMSA2; PSC2; PSC3; PSMA2

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UniProt ID: (Human) P25787, (Mouse) P49722

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Entrez Gene ID: (Human) 5683, (Mouse) 19166

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Function(s)
threonine-type endopeptidase activity protein binding endopeptidase activity peptidase activity hydrolase activity
Process(es)
MAPK cascade protein polyubiquitination stimulatory C-type lectin receptor signaling pathway antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent regulation of cellular amino acid metabolic process response to virus anaphase-promoting complex-dependent catabolic process tumor necrosis factor-mediated signaling pathway NIK/NF-kappaB signaling Fc-epsilon receptor signaling pathway proteasome-mediated ubiquitin-dependent protein catabolic process regulation of mRNA stability T cell receptor signaling pathway negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition Wnt signaling pathway, planar cell polarity pathway negative regulation of canonical Wnt signaling pathway positive regulation of canonical Wnt signaling pathway proteolysis ubiquitin-dependent protein catabolic process proteasomal ubiquitin-independent protein catabolic process proteolysis involved in cellular protein catabolic process
It has to be done as per old AB suggested Products section.
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