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  • Primary Antibodies ›
  • Cytochrome P450 Reductase Antibodies

OriGene

POR Monoclonal Antibody (OTI5B3), TrueMAB™

View all (37) Cytochrome P450 Reductase antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite POR Monoclonal Antibody (OTI5B3), TrueMAB™

  • Antibody Testing Data (22)
POR Antibody in Immunocytochemistry (ICC/IF)
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POR Antibody in Immunocytochemistry (ICC/IF)
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POR Antibody (CF500612) in ICC/IF

Immunofluorescent staining of HT29 cells using anti-POR mouse monoclonal antibody (TA500612). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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POR Antibody in Immunocytochemistry (ICC/IF)
POR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
POR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
POR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
POR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
POR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
POR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
POR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
POR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
POR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
POR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
POR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
POR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
POR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
POR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
POR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
POR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
POR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
POR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
POR Antibody in Western Blot (WB)
POR Antibody in Western Blot (WB)
POR Antibody in Flow Cytometry (Flow)
POR Monoclonal Antibody (OTI5B3), TrueMAB™

Product Details

CF500612

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50
-

Immunocytochemistry (ICC/IF)

1:50
-

Flow Cytometry (Flow)

1:100
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

OTI5B3

Immunogen

Full length human recombinant protein of human POR produced in HEK293T cell.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 8% trehalose

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

Target Information

This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CCR; CPR; CY DKFZp686G04235; DKFZp686G04235; FLJ26468; NADPH Cytochrome; NADPH--cytochrome P450 reductase; NADPH-dependent cytochrome P450 reductase; P450 (cytochrome) oxidoreductase; P450 Reductase

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Gene Aliases: CPR; CYPOR; P450R; POR

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UniProt ID: (Human) P16435

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Entrez Gene ID: (Human) 5447

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Function(s)
NADPH-hemoprotein reductase activity cytochrome-b5 reductase activity, acting on NAD(P)H protein binding nitric oxide dioxygenase activity electron carrier activity FMN binding hydrolase activity enzyme binding [methionine synthase] reductase activity iron-cytochrome-c reductase activity flavin adenine dinucleotide binding NADP binding
Process(es)
regulation of growth plate cartilage chondrocyte proliferation xenobiotic metabolic process response to nutrient carnitine metabolic process flavonoid metabolic process internal peptidyl-lysine acetylation fatty acid oxidation positive regulation of chondrocyte differentiation positive regulation of monooxygenase activity response to drug negative regulation of cysteine-type endopeptidase activity involved in apoptotic process nitrate catabolic process positive regulation of cholesterol biosynthetic process positive regulation of smoothened signaling pathway nitric oxide catabolic process oxidation-reduction process negative regulation of lipase activity demethylation cellular response to follicle-stimulating hormone stimulus cellular response to peptide hormone stimulus positive regulation of steroid hormone biosynthetic process cellular organofluorine metabolic process
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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