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  • Primary Antibodies ›
  • PLZF Antibodies

Invitrogen

PLZF Polyclonal Antibody

3 Published Figures
3 References
View all (18) PLZF antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite PLZF Polyclonal Antibody

  • Antibody Testing Data (5)
  • Published Figures (3)
PLZF Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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PLZF Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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PLZF Antibody (PA5-81949) in IHC (P)

Immunohistochemical analysis of PLZF in human Cerebral cortex using PLZF Polyclonal Antibody (Product # PA5-81949) shows moderate nuclear positivity in neuronal cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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PLZF Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PLZF Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PLZF Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PLZF Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PLZF Antibody in Western Blot (WB)
PLZF Antibody in Immunohistochemistry, Flow Cytometry (IHC, Flow)
PLZF Antibody in Immunohistochemistry (IHC)
PLZF Antibody in Immunohistochemistry (IHC)
PLZF Polyclonal Antibody

Product Details

PA5-81949

Applications
Tested Dilution
Publications

Western Blot (WB)

0.04-0.4 µg/mL
-

Immunohistochemistry (IHC)

-
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunohistochemistry (Frozen) (IHC (F))

-
View 1 publication 1 publication

Flow Cytometry (Flow)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human

Published species

Pig

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ZBTB16. Recombinant protein control fragment (Product #RP-100699).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2789110

Product Specific Information

Immunogen sequence: HYTLDFLSPK TFQQILEYAY TATLQAKAED LDDLLYAAEI LEIEYLEEQC LKMLETIQAS DDNDTEATMA DGGAEEEEDR KARYLKNIFI SKHSSEESGY ASVAGQSLPG PMVDQSPSVS TSFGLSA

Target Information

This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: promyelocytic leukaemia zinc finger; Promyelocytic leukemia zinc finger protein; Zinc finger and BTB domain-containing protein 16; Zinc finger protein 145; zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia); Zinc finger protein PLZF

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Gene Aliases: PLZF; ZBTB16; ZNF145

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UniProt ID: (Human) Q05516

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Entrez Gene ID: (Human) 7704

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Function(s)
RNA polymerase II distal enhancer sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding DNA binding protein binding protein C-terminus binding protein domain specific binding identical protein binding protein homodimerization activity metal ion binding
Process(es)
negative regulation of transcription from RNA polymerase II promoter mesonephros development transcription, DNA-templated apoptotic process central nervous system development negative regulation of cell proliferation embryonic pattern specification anterior/posterior pattern specification protein ubiquitination hemopoiesis myeloid cell differentiation positive regulation of chondrocyte differentiation protein localization to nucleus embryonic hindlimb morphogenesis forelimb morphogenesis embryonic digit morphogenesis positive regulation of apoptotic process positive regulation of fat cell differentiation negative regulation of myeloid cell differentiation positive regulation of ossification negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated male germ-line stem cell asymmetric division positive regulation of NK T cell differentiation cartilage development positive regulation of cartilage development
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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