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  • Primary Antibodies ›
  • PDE3B Antibodies

Proteintech

PDE3B Polyclonal Antibody

1 Reference
View all (29) PDE3B antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite PDE3B Polyclonal Antibody

  • Antibody Testing Data (1)
PDE3B Antibody in Immunoprecipitation (IP)
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PDE3B Antibody in Immunoprecipitation (IP)
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PDE3B Antibody (25290-1-AP) in IP

IP result of anti-PDE3B (IP:25290-1-AP, 5ug; Detection:25290-1-AP 1:300) with HeLa cells lysate 800ug. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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PDE3B Antibody in Immunoprecipitation (IP)
PDE3B Polyclonal Antibody

Product Details

25290-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

-
View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PDE3B Fusion Protein Ag18064 (321-670 aa encoded by BC136565)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.31 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: CISREQMIL WDWDLKQWYK PHYQNSGGGN GVDLSVLNEA RNMVSDLLTD PSLPPQVISS LRSISSLMGA FSGSCRPKIN PLTPFPGFYP CSEIEDPAEK GDRKLNKGLN RNSLPTPQLR RSSGTSGLLP VEQSSRWDRN NGKRPHQEFG ISSQGCYLNG PFNSNLLTIP KQRSSSVSLT HHVGLRRAGV LSSLSPVNSS NHGPVSTGSL TNRSPIEFPD TADFLNKPSV ILQRSLGNAP NTPDFYQQLR NSDSNLCNSC GHQMLKYVST SESDGTDCCS GKSGEEENIF SKESFKLMET QQEEETEKKD SRKLFQEGDK WLTEEAQSEQ QTNIEQEVSL DLILVEEYDS L (321-670 aa encoded by BC136565)

Target Information

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: CGI-PDE B; CGIP1; CGIPDE1; cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B; Cyclic GMP-inhibited phosphodiesterase B; cyclic nucleotide phosphodiesterase; phosphodiesterase 3B, cGMP-inhibited

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Gene Aliases: cGIPDE1; HcGIP1; PDE3B

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UniProt ID: (Human) Q13370

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Entrez Gene ID: (Human) 5140

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Function(s)
3',5'-cyclic-nucleotide phosphodiesterase activity 3',5'-cyclic-AMP phosphodiesterase activity cGMP-inhibited cyclic-nucleotide phosphodiesterase activity protein binding protein kinase B binding metal ion binding 3',5'-cyclic-GMP phosphodiesterase activity
Process(es)
angiogenesis cAMP catabolic process negative regulation of cell adhesion signal transduction negative regulation of angiogenesis cellular response to insulin stimulus negative regulation of cell adhesion mediated by integrin negative regulation of cAMP-mediated signaling negative regulation of lipid catabolic process
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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