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  • Primary Antibodies ›
  • PDE1B Antibodies

OriGene

PDE1B Monoclonal Antibody (OTI1D6), TrueMAB™

View all (23) PDE1B antibodies

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Datasheet
Protocols
Questions & Answers

Cite PDE1B Monoclonal Antibody (OTI1D6), TrueMAB™

  • Antibody Testing Data (2)
PDE1B Antibody in Immunocytochemistry (ICC/IF)
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PDE1B Antibody in Immunocytochemistry (ICC/IF)
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PDE1B Antibody (CF503336) in ICC/IF

Anti-PDE1B mouse monoclonal antibody (TA503336) Immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDE1B(RC206588). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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PDE1B Antibody in Immunocytochemistry (ICC/IF)
PDE1B Antibody in Western Blot (WB)
PDE1B Monoclonal Antibody (OTI1D6), TrueMAB™

Product Details

CF503336

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000
-

Immunocytochemistry (ICC/IF)

1:100
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

OTI1D6

Immunogen

Full length human recombinant protein of human PDE1B produced in HEK293T cell.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 8% trehalose

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

Target Information

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 63 a Cam PDE; 63 a Cam-PDE; 63 kDa Cam-PDE; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; calmodulin-stimulated phosphodiesterase PDE1B1; Cam PDE 1B; Cam PDE1B; Cam-PDE 1B; Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; epididymis secretory sperm binding protein Li 79p; PDE 1B; PDES 1B; Phosphodiesterase; phosphodiesterase 1B, calmodulin-dependent; presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B

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Gene Aliases: HEL-S-79p; PDE1B; PDE1B1; PDES1B

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UniProt ID: (Human) Q01064

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Entrez Gene ID: (Human) 5153

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Function(s)
3',5'-cyclic-AMP phosphodiesterase activity calmodulin-dependent cyclic-nucleotide phosphodiesterase activity protein binding calmodulin binding metal ion binding 3',5'-cyclic-GMP phosphodiesterase activity calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity
Process(es)
regulation of neurotransmitter levels response to amphetamine cAMP catabolic process apoptotic process signal transduction locomotory behavior visual learning monocyte differentiation cellular response to macrophage colony-stimulating factor stimulus regulation of dopamine metabolic process serotonin metabolic process cGMP catabolic process cellular response to granulocyte macrophage colony-stimulating factor stimulus
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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