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Invitrogen
PDE11A Polyclonal Antibody
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Product Details
PA1-31147
Species Reactivity
Host/Isotype
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Type
Immunogen
Conjugate
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Product Specific Information
Recommended positive controls: Rat testis, skeletal muscle, kidney and brain.
Target Information
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: cAMP and cGMP cyclic nucleotide phosphodiesterase 11A; cAMP and cGMP phosphodiesterase 11A; Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A; FLJ23693; MGC133355; MGC133356
Gene Aliases: 6330414F14Rik; A630086N24Rik; Gm350; PDE11A; PDE11A1; PPNAD2
UniProt ID: (Human) Q9HCR9, (Mouse) P0C1Q2, (Rat) Q8VID6
Entrez Gene ID: (Human) 50940, (Mouse) 241489, (Rat) 140928
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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