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  • Primary Antibodies ›
  • PANK1/PANK2/PANK3 Antibodies

Proteintech

PANK1/2/3 Polyclonal Antibody

1 Reference

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite PANK1/2/3 Polyclonal Antibody

  • Antibody Testing Data (9)
PANK1/2/3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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PANK1/2/3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 9

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PANK1/2/3 Antibody (12466-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using 12466-1-AP (PANK1/2/3 antibody at dilution of 1:100 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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PANK1/2/3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PANK1/2/3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PANK1/2/3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PANK1/2/3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PANK1/2/3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PANK1/2/3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PANK1/2/3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PANK1/2/3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
PANK1/2/3 Antibody in Western Blot (WB)
PANK1/2/3 Polyclonal Antibody

Product Details

12466-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PANK1/2/3 Fusion Protein Ag3140 (61-370 aa encoded by BC013705)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: TGIRDVHLE LKDLTLFGRR GNLHFIRFPT QDLPTFIQMG RDKNFSTLQT VLCATGGGAY KFEKDFRTIG NLHLHKLDEL DCLVKGLLYI DSVSFNGQAE CYYFANASEP ERCQKMPFNL DDPYPLLVVN IGSGVSILAV HSKDNYKRVT GTSLGGGTFL GLCSLLTGCE SFEEALEMAS KGDSTQADKL VRDIYGGDYE RFGLPGWAVA SSFGNMIYKE KRESVSKEDL ARATLVTITN NIGSVARMCA VNEKINRVVF VGNFLRVNTL SMKLLAYALD YWSKGQLKAL FLEHEGYFGA VGALLGLPNF S (61-370 aa encoded by BC013705)

Target Information

This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is expressed most abundantly in the liver.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Hallervorden-Spatz syndrome; hPanK; hPanK2; hPanK3; mPank; mPanK3; Pantothenate kinase 1; pantothenate kinase 2 (Hallervorden-Spatz syndrome); Pantothenate kinase 2, mitochondrial; Pantothenate kinase 3; Pantothenic acid kinase 1; Pantothenic acid kinase 2; Pantothenic acid kinase 3

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Gene Aliases: 4933409I19Rik; AI642621; C20orf48; HARP; HSS; NBIA1; PANK; PANK1; Pank1b; PANK2; PANK3; PKAN

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UniProt ID: (Human) Q8TE04, (Human) Q9BZ23, (Human) Q9H999, (Mouse) Q8K4K6, (Mouse) Q7M753, (Mouse) Q8R2W9

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Entrez Gene ID: (Human) 53354, (Human) 80025, (Human) 79646, (Mouse) 75735, (Rat) 294088, (Rat) 296167, (Mouse) 74450, (Mouse) 211347, (Rat) 360511

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Function(s)
pantothenate kinase activity ATP binding nucleotide binding kinase activity transferase activity
Process(es)
coenzyme biosynthetic process coenzyme A biosynthetic process phosphorylation spermatid development aerobic respiration regulation of mitochondrial membrane potential mitochondrion morphogenesis pantothenate metabolic process regulation of fatty acid metabolic process regulation of triglyceride metabolic process regulation of bile acid metabolic process
It has to be done as per old AB suggested Products section.
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