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Proteintech
P62/SQSTM1 Monoclonal Antibody (1H5C1)
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Product Details
66184-1-IG
Species Reactivity
Published species
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Conjugate
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Product Specific Information
The molecular weight of p62 is predicted as 48/ 38 kDa, while western blot analyses using this antibody demonstrate the major band around 60-62 kDa in various tissues.
Immunogen sequence: MASLTVKAY LLGKEDAARE IRRFSFCCSP EPEAEAEAAA GPGPCERLLS RVAALFPALR PGGFQAHYRD EDGDLVAFSS DEELTMAMSY VKDDIFRIYI KEKKECRRDH RPPCAQEAPR NMVHPNVICD GCNGPVVGTR YKCSVCPDYD LCSVCEGKGL HRGHTKLAFP SPFGHLSEGF SHSRWLRKVK HGHFGWPGWE MGPPGNWSPR PPRAGEARPG PTAESASGPS EDPSVNFLKN VGESVAAALS PLGIEVDIDV EHGGKRSRLT PVSPESSSTE EKSSSQPSSC CSDPSKPGGN VEGATQSLAE QMRKIALESE GRPEEQMESD NCSGGDDDWT HLSSKEVDPS TGELQSLQMP ESEGPSSLDP SQEGPTGLKE AALYPHLPPE ADPRLIESLS QMLSMGFSDE GGWLTRLLQT KNYDIGAALD TIQYSKHPPP L (1-440 aa encoded by BC017222)
Target Information
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: EBI3-associated protein of 60 kDa; EBI3-associated protein p60; EBIAP; oxidative stress induced like; p62; phosphotyrosine independent ligand for the Lck SH2 domain p62; Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa; Sequestosome-1; Ubiquitin-binding protein p62
Gene Aliases: A170; FTDALS3; ORCA; OSIL; p60; p62; p62B; PDB3; SQSTM1; ZIP3
UniProt ID: (Human) Q13501
Entrez Gene ID: (Human) 8878
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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