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  • Primary Antibodies ›
  • TNFRSF11B Antibodies

Fabgennix

Osteoprotegerin Polyclonal Antibody, Biotin

View all (24) TNFRSF11B antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite Osteoprotegerin Polyclonal Antibody, Biotin

Osteoprotegerin Polyclonal Antibody, Biotin

Product Details

OPG-BIOTIN

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

Immunohistochemistry (IHC)

1:50-1:250
-

ELISA (ELISA)

1:10,000
-

Immunoprecipitation (IP)

1:50-1:250
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide taken within amino acid region 350-400 on human Tumor necrosis factor receptor superfamily member 11B protein.
View immunogen

Conjugate

Biotin Biotin Biotin

Form

Liquid

Concentration

0.5-1.5 mg/mL

Purification

Affinity chromatography

Storage buffer

proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: MGC29565; Osteoclastogenesis inhibitory factor; Osteoprotegerin; soluble OPG; soluble Osteoprotegerin; sOPG; Tumor necrosis factor receptor superfamily member 11B; tumor necrosis factor receptor superfamily, member 11b

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Gene Aliases: OCIF; OPG; PDB5; TNFRSF11B; TR1

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UniProt ID: (Human) O00300, (Mouse) O08712, (Rat) O08727

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Entrez Gene ID: (Human) 4982, (Mouse) 18383, (Rat) 25341

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Function(s)
receptor activity tumor necrosis factor-activated receptor activity cytokine activity molecular_function
Process(es)
apoptotic process signal transduction extracellular matrix organization negative regulation of odontogenesis of dentin-containing tooth negative regulation of bone resorption skeletal system development inflammatory response immune response response to nutrient response to magnesium ion response to lipopolysaccharide tumor necrosis factor-mediated signaling pathway regulation of cell proliferation response to drug regulation of apoptotic process positive regulation of MAPK cascade response to estrogen response to arsenic-containing substance apoptotic signaling pathway response to inorganic substance
It has to be done as per old AB suggested Products section.
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