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  • Primary Antibodies ›
  • OX40 (CD134) Antibodies

Invitrogen

OX40 Monoclonal Antibody (OX40), Biotin

View all (83) OX40 (CD134) antibodies

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Datasheet
Protocols
Questions & Answers

Cite OX40 Monoclonal Antibody (OX40), Biotin

  • Antibody Testing Data (1)
OX40 Antibody in Flow Cytometry (Flow)
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OX40 Antibody in Flow Cytometry (Flow)
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OX40 Antibody (MA5-17497) in Flow

Flow cytometric analysis of Con-A activated Spleen Cells stained using anti-CD134/OX-40 Monoclonal Antibody (Product # MA5-17497) at a 0.2 µg/10^6 cells dilution. The Isotype control was a Mouse IgG2b {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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OX40 Antibody in Flow Cytometry (Flow)
OX40 Monoclonal Antibody (OX40), Biotin

Product Details

MA5-17497

Applications
Tested Dilution
Publications

Immunohistochemistry (Frozen) (IHC (F))

Assay-dependent
-

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells
-
Product Specifications

Species Reactivity

Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OX40

Immunogen

Phytohaemagglutinin-activated rat lymph node cells
View immunogen

Conjugate

Biotin Biotin Biotin
  • Unconjugated
  • FITC
  • PE 
  • Request custom conjugation

Form

Liquid

Concentration

0.1 mg/mL

Purification

Protein G

Storage buffer

PBS with 4-5mg/mL BSA

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2538887

Product Specific Information

MA5-17497 targets CD134/OX-40 in FACS and IHC (F) applications and shows reactivity with Rat samples.

The MA5-17497 immunogen is phytohaemagglutinin-activated rat lymph node cells.

Target Information

OX40 is a protein receptor found on the surface of T cells, a type of white blood cell that plays a crucial role in the immune system. When activated, OX40 promotes the proliferation and survival of T cells, leading to a stronger immune response against cancer cells and infectious agents. OX40 agonists, which are drugs that activate OX40, have shown promising results in preclinical and clinical studies as a potential immunotherapy for cancer. They can enhance the efficacy of other cancer treatments such as chemotherapy and checkpoint inhibitors, and may also have applications in autoimmune diseases and allergies.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CD134; MRC OX40; OX40 antigen; OX40L receptor; Tax-transcriptionally activated glycoprotein 1; tumor necrosis factor (ligand) superfamily member 4; Tumor necrosis factor receptor superfamily member 4; tumor necrosis factor superfamily, member 4

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Gene Aliases: Ox40; Tnfrsf4; Txgp1; Txgp1l

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UniProt ID: (Rat) P15725

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Entrez Gene ID: (Rat) 25572

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Function(s)
tumor necrosis factor-activated receptor activity
Process(es)
inflammatory response cellular defense response programmed cell death positive regulation of B cell proliferation tumor necrosis factor-mediated signaling pathway T cell proliferation regulation of apoptotic process negative regulation of sequence-specific DNA binding transcription factor activity regulation of protein kinase activity negative regulation of transcription, DNA-templated negative regulation of cytokine secretion positive regulation of immunoglobulin secretion negative regulation of activation-induced cell death of T cells negative regulation of extrinsic apoptotic signaling pathway
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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